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VYNE Therapeutics
VYNE

Overview Fund Activity

46 hedge funds and large institutions have $13.4M invested in VYNE Therapeutics in 2025 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 8 increasing their positions, 12 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
46
Holders Change
+8
Holders Change %
+21.05%
% of All Funds
0.62%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
15
Increased
8
Reduced
12
Closed
7
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
CAM
Cormorant Asset Management
Massachusetts
$2.26M
2
KCM
Kennedy Capital Management
Missouri
$942K
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$1.06M
4
IC
Ikarian Capital
Texas
$479K
5
Jane Street
Jane Street
New York
$206K

Top Sellers

1
EAM
Eventide Asset Management
Massachusetts
$0
2
EAM
Exome Asset Management
New York
$345K
3
PHP
Parkman Healthcare Partners
Connecticut
$0
4
Renaissance Technologies
Renaissance Technologies
New York
$17.4K
5
PCM
Prelude Capital Management
New York
$107K
Name Holding Trade Value Shares
Change 		Shares
Change %
CAM
1
Cormorant Asset Management
Massachusetts
$2.26M +$2.26M +1,370,938 New
Citadel Advisors
2
Citadel Advisors
Florida
$1.72M -$99.4K -60,259 -5%
ACA
3
Acorn Capital Advisors
New York
$1.22M -$81.5K -49,366 -6%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$1.06M +$495K +300,000 +87%
DCM
5
DAFNA Capital Management
California
$1.05M – – –
KCM
6
Kennedy Capital Management
Missouri
$942K +$942K +570,740 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$819K +$34.1K +20,647 +4%
PAI
8
Palo Alto Investors
California
$735K – – –
PSC
9
Patient Square Capital
California
$523K +$99K +60,000 +23%
IC
10
Ikarian Capital
Texas
$479K +$479K +290,000 New
EAM
11
Exome Asset Management
New York
$345K -$419K -253,831 -55%
SSA
12
Schonfeld Strategic Advisors
New York
$267K +$127K +76,973 +91%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$220K -$266 -161 -0.1%
Jane Street
14
Jane Street
New York
$206K +$206K +124,822 New
TAM
15
TFG Asset Management
Cayman Islands
$190K +$190K +115,384 New
BFM
16
Boothbay Fund Management
New York
$176K +$176K +106,459 New
Squarepoint
17
Squarepoint
New York
$129K +$129K +78,474 New
BCM
18
Bridgeway Capital Management
Texas
$127K +$41.3K +25,000 +48%
PCM
19
Prelude Capital Management
New York
$107K -$127K -76,918 -54%
Susquehanna International Group
20
Susquehanna International Group
Pennsylvania
$95.4K +$86 +52 +0.1%
XT
21
XTX Topco
Cayman Islands
$93.9K +$39.4K +23,856 +72%
SCA
22
STALEY CAPITAL ADVISERS
Pennsylvania
$84.9K – – –
HIS
23
Harvest Investment Services
Illinois
$84.7K +$84.7K +51,326 New
BlackRock
24
BlackRock
New York
$73.3K -$63K -38,174 -46%
HF
25
HRT Financial
New York
$69K +$25.9K +15,795 +60%
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