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VYNE Therapeutics

45 hedge funds and large institutions have $8.63M invested in VYNE Therapeutics in 2026 Q1 according to their latest regulatory filings, with 8 funds opening new positions, 11 increasing their positions, 5 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

120% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 5

81% more capital invested

Capital invested by funds: $4.77M → $8.63M (+$3.86M)

60% more first-time investments, than exits

New positions opened: 8 | Existing positions closed: 5

18.64% more ownership

Funds ownership: 24.73%43.37% (+19%)

2% more funds holding

Funds holding: 4445 (+1)

Holders
45
Holders Change
+1
Holders Change %
+2.27%
% of All Funds
0.55%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
8
Increased
11
Reduced
5
Closed
5
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
AFM
1
Anson Funds Management
Texas
$1.49M +$707K +1,211,826 +95%
NCM
2
Nantahala Capital Management
Connecticut
$1.2M +$583K +1,000,000 +100%
LCM
3
Lynx1 Capital Management
Puerto Rico
$973K +$950K +1,628,700 New
SC
4
Shay Capital
New York
$962K -$8.23K -14,107 -0.9%
ACM
5
ADAR1 Capital Management
Texas
$636K +$473K +810,108 +319%
TC
6
T3 Companies
New York
$565K
B
7
Braidwell
Connecticut
$547K +$534K +916,077 New
Citadel Advisors
8
Citadel Advisors
Florida
$307K +$282K +483,917 +1,585%
KCA
9
KVP Capital Advisors
California
$299K
Two Sigma Investments
10
Two Sigma Investments
New York
$255K +$120K +206,412 +94%
Acadian Asset Management
11
Acadian Asset Management
Massachusetts
$228K -$150K -256,695 -40%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$193K +$56.9K +97,559 +43%
IC
13
Ikarian Capital
Texas
$158K
VCM
14
Vanguard Capital Management
Pennsylvania
$158K +$154K +264,557 New
VFT
15
Vanguard Fiduciary Trust
Pennsylvania
$110K +$107K +183,443 New
UBS Group
16
UBS Group
Switzerland
$108K +$68.3K +117,023 +186%
XT
17
XTX Topco
Cayman Islands
$94.6K +$46.3K +79,356 +100%
RC
18
Rangeley Capital
Connecticut
$70.5K +$10.5K +18,064 +18%
Jane Street
19
Jane Street
New York
$57.1K +$13.6K +23,289 +32%
BFM
20
Boothbay Fund Management
New York
$48.6K
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$34.5K -$24.8K -42,557 -42%
SCA
22
STALEY CAPITAL ADVISERS
Pennsylvania
$30.8K
BlackRock
23
BlackRock
New York
$26.5K
FIA
24
FNY Investment Advisers
New York
$20K +$5.83K +10,000 +40%
HF
25
HRT Financial
New York
$16K +$16.1K +27,569 New

VYNE Hedge Fund Activity: Q1 2026 in Review

45 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in VYNE Therapeutics (VYNE) for Q1 2026, worth a combined $8.63M — up 81% from $4.77M a quarter earlier.

Buyers outnumbered sellers: 8 funds opened new VYNE positions and 5 closed out — a net gain of 3 holders — while 11 added to existing stakes and 5 trimmed.

The largest buyer was Lynx1 Capital Management, opening a new position worth an estimated $950K. The largest seller was Acadian Asset Management, cutting an estimated $150K.

  • 45 institutional investors held VYNE Therapeutics (VYNE) as of Q1 2026, up from 44 in Q4 2025.
  • Funds reported $8.63M of VYNE Therapeutics stock for Q1 2026, up 81% quarter-over-quarter.
  • 8 funds opened new VYNE Therapeutics positions in Q1 2026 and 5 closed out, a net change of +3 holders.
  • The largest VYNE Therapeutics buyer in Q1 2026 was Lynx1 Capital Management, an estimated $950K added.
  • The largest VYNE Therapeutics seller in Q1 2026 was Acadian Asset Management, an estimated $150K sold.

Based on aggregated 13F filings for Q1 2026.