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VYNE Therapeutics
VYNE

Overview Fund Activity

45 hedge funds and large institutions have $13.3M invested in VYNE Therapeutics in 2025 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 7 increasing their positions, 12 reducing their positions, and 7 closing their positions.

Holders
45
Holders Change
+7
Holders Change %
+18.42%
% of All Funds
0.6%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
15
Increased
7
Reduced
12
Closed
7
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
CAM
1
Cormorant Asset Management
Massachusetts
$2.26M
2
KCM
2
Kennedy Capital Management
Missouri
$942K
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$1.06M
4
IC
4
Ikarian Capital
Texas
$479K
5
Jane Street
5
Jane Street
New York
$206K

Top Sellers

1
EAM
1
Eventide Asset Management
Massachusetts
$0
2
EAM
2
Exome Asset Management
New York
$345K
3
PHP
3
Parkman Healthcare Partners
Connecticut
$0
4
Renaissance Technologies
4
Renaissance Technologies
New York
$17.4K
5
PCM
5
Prelude Capital Management
New York
$107K
Name Market Value Shares Shares
Change 		Shares
Change %
CAM
1
Cormorant Asset Management
Massachusetts
$2.26M 1,370,938 +1,370,938 New
Citadel Advisors
2
Citadel Advisors
Florida
$1.72M 1,040,070 -60,259 -5%
ACA
3
Acorn Capital Advisors
New York
$1.22M 736,572 -49,366 -6%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$1.06M 644,134 +300,000 +87%
DCM
5
DAFNA Capital Management
California
$1.05M 636,103 – –
KCM
6
Kennedy Capital Management
Missouri
$942K 570,740 +570,740 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$819K 496,297 +20,647 +4%
PAI
8
Palo Alto Investors
California
$735K 445,434 – –
PSC
9
Patient Square Capital
California
$523K 317,033 +60,000 +23%
IC
10
Ikarian Capital
Texas
$479K 290,000 +290,000 New
EAM
11
Exome Asset Management
New York
$345K 208,970 -253,831 -55%
SSA
12
Schonfeld Strategic Advisors
New York
$267K 161,951 +76,973 +91%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$220K 133,329 -161 -0.1%
Jane Street
14
Jane Street
New York
$206K 124,822 +124,822 New
TAM
15
TFG Asset Management
Cayman Islands
$190K 115,384 +115,384 New
BFM
16
Boothbay Fund Management
New York
$176K 106,459 +106,459 New
Squarepoint
17
Squarepoint
New York
$129K 78,474 +78,474 New
BCM
18
Bridgeway Capital Management
Texas
$127K 76,958 +25,000 +48%
PCM
19
Prelude Capital Management
New York
$107K 64,584 -76,918 -54%
XT
20
XTX Topco
Cayman Islands
$93.9K 56,908 +23,856 +72%
SCA
21
STALEY CAPITAL ADVISERS
Pennsylvania
$84.9K 51,472 – –
HIS
22
Harvest Investment Services
Illinois
$84.7K 51,326 +51,326 New
BlackRock
23
BlackRock
New York
$73.3K 44,405 -38,174 -46%
HF
24
HRT Financial
New York
$69K 42,037 +15,795 +60%
VCIM
25
Velan Capital Investment Management
Georgia
$49.5K 30,000 +30,000 New
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