|
1
|
|
$71.9M
|
-$5.04M
|
-301,157
|
-7%
|
|
|
2
|
Palo Alto Investors
Palo Alto,
California
|
$70M
|
–
|
–
|
–
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$52.9M
|
+$5.15M
|
+307,933
|
+11%
|
|
|
4
|
Consonance Capital Management
New York
|
$51.8M
|
+$51.4M
|
+3,072,275
|
New
|
|
|
5
|
Avoro Capital Advisors
New York
|
$46.8M
|
+$22.9M
|
+1,366,245
|
+97%
|
|
|
6
|
Armistice Capital
New York
|
$43.8M
|
-$1.31M
|
-78,000
|
-3%
|
|
|
7
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$38.4M
|
+$172K
|
+10,256
|
+0.5%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$31.7M
|
-$4.2M
|
-251,137
|
-12%
|
|
|
9
|
Renaissance Technologies
New York
|
$27.6M
|
+$3.43M
|
+205,200
|
+14%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$23.6M
|
+$20.2M
|
+1,205,459
|
+620%
|
|
|
11
|
Rothschild & Co Asset Management US
Stamford,
Connecticut
|
$22.8M
|
-$327K
|
-19,515
|
-1%
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$22.1M
|
–
|
–
|
–
|
|
|
13
|
|
$21.7M
|
+$21.6M
|
+1,290,636
|
New
|
|
|
14
|
|
$20.8M
|
+$3.14M
|
+187,413
|
+18%
|
|
|
15
|
Millennium Management
New York
|
$16.8M
|
-$2.2M
|
-131,290
|
-12%
|
|
|
16
|
Stonepine Capital Management
Bend,
Oregon
|
$16.6M
|
+$1.67M
|
+99,584
|
+11%
|
|
|
17
|
Cormorant Asset Management
Boston,
Massachusetts
|
$16.1M
|
+$16M
|
+957,821
|
New
|
|
|
18
|
Prudential Financial
Newark,
New Jersey
|
$14.3M
|
+$2.41M
|
+143,770
|
+20%
|
|
|
19
|
Teachers Advisors
New York
|
$12M
|
+$149K
|
+8,900
|
+1%
|
|
|
20
|
Baker Bros. Advisors
New York
|
$10.1M
|
+$2.95M
|
+176,470
|
+42%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$9.85M
|
+$113K
|
+6,730
|
+1%
|
|
|
22
|
Man Group
London,
United Kingdom
|
$8.71M
|
+$8.65M
|
+516,600
|
New
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$8.7M
|
+$1.16M
|
+69,600
|
+16%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$8.44M
|
+$1.71M
|
+102,100
|
+26%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$6.44M
|
-$1.67M
|
-99,875
|
-21%
|
|
