|
1
|
Deerfield Management
New York
|
$55.8M
|
+$12.1M
|
+1,212,534
|
+25%
|
|
|
2
|
Palo Alto Investors
Palo Alto,
California
|
$37.5M
|
+$337K
|
+33,800
|
+0.8%
|
|
|
3
|
|
$36.7M
|
–
|
–
|
–
|
|
|
4
|
Great Point Partners
Greenwich,
Connecticut
|
$19.6M
|
+$3.84M
|
+385,101
|
+22%
|
|
|
5
|
Stonepine Capital Management
Bend,
Oregon
|
$17.9M
|
+$19.1M
|
+1,918,929
|
New
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$15.7M
|
-$7.98M
|
-799,413
|
-32%
|
|
|
7
|
Armistice Capital
New York
|
$15.2M
|
+$8.68M
|
+870,000
|
+114%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$15.1M
|
-$618K
|
-61,938
|
-4%
|
|
|
9
|
Millennium Management
New York
|
$14.3M
|
-$2.59M
|
-259,698
|
-14%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$13.8M
|
+$237K
|
+23,797
|
+2%
|
|
|
11
|
|
$13.4M
|
-$1.36M
|
-136,092
|
-9%
|
|
|
12
|
Avoro Capital Advisors
New York
|
$11.7M
|
-$8.62M
|
-863,784
|
-41%
|
|
|
13
|
Bank of Montreal
Toronto,
Ontario, Canada
|
$11.3M
|
+$2.28M
|
+228,074
|
+23%
|
|
|
14
|
Consonance Capital Management
New York
|
$10.2M
|
-$3.42M
|
-343,100
|
-24%
|
|
|
15
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$10.1M
|
+$823K
|
+82,474
|
+8%
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$10M
|
+$216K
|
+21,677
|
+2%
|
|
|
17
|
Kingdon Capital Management
New York
|
$8.7M
|
-$10.1M
|
-1,008,699
|
-52%
|
|
|
18
|
|
$8.4M
|
+$4.2M
|
+421,079
|
+87%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$4.71M
|
+$286K
|
+28,620
|
+6%
|
|
|
20
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.3M
|
-$512K
|
-51,339
|
-10%
|
|
|
21
|
|
$4.16M
|
+$2.67M
|
+267,765
|
+150%
|
|
|
22
|
Skandinaviska Enskilda Banken (SEB)
Stockholm,
Sweden
|
$4.08M
|
+$4.21M
|
+422,300
|
New
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$4.01M
|
+$552K
|
+55,362
|
+15%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$3.24M
|
+$661K
|
+66,261
|
+24%
|
|
|
25
|
Renaissance Technologies
New York
|
$3.14M
|
+$3.37M
|
+337,390
|
New
|
|
