United Therapeutics
UTHR
708 hedge funds and large institutions have $17.2B invested in United Therapeutics in 2025 Q3 according to their latest regulatory filings, with 112 funds opening new positions, 212 increasing their positions, 286 reducing their positions, and 66 closing their positions.
89% more funds holding in top 10
Funds holding in top 10: 9 → 17 (+8)
70% more first-time investments, than exits
New positions opened: 112 | Existing positions closed: 66
36% more capital invested
Capital invested by funds: $12.6B → $17.2B (+$4.54B)
6% more funds holding
Funds holding: 671 → 708 (+37)
6.63% less ownership
Funds ownership: 97.48% → 90.85% (-6.6%)
26% less repeat investments, than reductions
Existing positions increased: 212 | Existing positions reduced: 286
51% less call options, than puts
Call options by funds: $622M | Put options by funds: $1.27B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
DGM
Darwin Global Management
St. Helier,
Jersey
|
+$252M |
| 2 |
Citigroup
New York
|
+$171M |
| 3 |
EP
Eversept Partners
New York
|
+$65.2M |
| 4 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$62.7M |
| 5 |
Millennium Management
New York
|
+$61M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Caisse de Depot et Placement du Quebec (CDPQ)
Montreal,
Quebec, Canada
|
-$129M |
| 2 |
ACA
Avoro Capital Advisors
New York
|
-$117M |
| 3 |
Victory Capital Management
San Antonio,
Texas
|
-$96.5M |
| 4 |
AQR Capital Management
Greenwich,
Connecticut
|
-$96.4M |
| 5 |
Invesco
Atlanta,
Georgia
|
-$83.2M |
UTHR Hedge Fund Activity: Q3 2025 in Review
708 of the 7,638 institutional investors tracked by Wall St. Rank reported a position in United Therapeutics (UTHR) for Q3 2025, worth a combined $17.2B — up 36% from $12.6B a quarter earlier.
Buyers outnumbered sellers: 112 funds opened new UTHR positions and 66 closed out — a net gain of 46 holders — while 212 added to existing stakes and 286 trimmed.
The largest buyer was Darwin Global Management, opening a new position worth an estimated $252M. The largest seller was Caisse de Depot et Placement du Quebec (CDPQ), cutting an estimated $129M.
- 708 institutional investors held United Therapeutics (UTHR) as of Q3 2025, up from 671 in Q2 2025.
- Funds reported $17.2B of United Therapeutics stock for Q3 2025, up 36% quarter-over-quarter.
- 112 funds opened new United Therapeutics positions in Q3 2025 and 66 closed out, a net change of +46 holders.
- The largest United Therapeutics buyer in Q3 2025 was Darwin Global Management, an estimated $252M added.
- The largest United Therapeutics seller in Q3 2025 was Caisse de Depot et Placement du Quebec (CDPQ), an estimated $129M sold.
Based on aggregated 13F filings for Q3 2025.