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United Therapeutics

670 hedge funds and large institutions have $12.6B invested in United Therapeutics in 2025 Q2 according to their latest regulatory filings, with 77 funds opening new positions, 284 increasing their positions, 218 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 218

28% more call options, than puts

Call options by funds: $134M | Put options by funds: $105M

8% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 71

0% less funds holding

Funds holding: 671670 (-1)

2.63% less ownership

Funds ownership: 100.11%97.48% (-2.6%)

9% less capital invested

Capital invested by funds: $13.9B → $12.6B (-$1.22B)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

Holders
670
Holders Change
-1
Holders Change %
-0.15%
% of All Funds
8.82%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
77
Increased
284
Reduced
218
Closed
71
Calls
$134M
Puts
$105M
Net Calls
+$29M
Net Calls Change
+$30.3M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$1.53B -$33.6M -112,384 -2%
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.28B -$2.48M -8,287 -0.2%
ACA
3
Avoro Capital Advisors
New York
$681M -$91.2M -305,000 -11%
State Street
4
State Street
Massachusetts
$623M -$18.9M -63,197 -3%
Renaissance Technologies
5
Renaissance Technologies
New York
$609M +$3.62M +12,100 +0.6%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$415M -$174M -583,480 -29%
AQR Capital Management
7
AQR Capital Management
Connecticut
$363M +$109M +364,713 +40%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$344M -$7.06M -23,628 -2%
Invesco
9
Invesco
Georgia
$254M +$125M +419,588 +90%
LSV Asset Management
10
LSV Asset Management
Illinois
$248M -$11.3M -37,700 -4%
AssetMark Inc
11
AssetMark Inc
California
$206M +$59M +197,384 +38%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$165M -$15.2M -50,977 -8%
DM
13
Deerfield Management
New York
$155M +$79.3M +265,400 +96%
Pacer Advisors
14
Pacer Advisors
Pennsylvania
$146M -$11.5M -38,355 -7%
Caisse de Depot et Placement du Quebec (CDPQ)
15
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$139M +$1.5M +5,024 +1%
Norges Bank
16
Norges Bank
Norway
$136M +$2.54M +8,515 +2%
Northern Trust
17
Northern Trust
Illinois
$130M -$5.72M -19,146 -4%
Fidelity Investments
18
Fidelity Investments
Massachusetts
$122M -$215M -720,363 -63%
Morgan Stanley
19
Morgan Stanley
New York
$114M -$6.96M -23,281 -6%
Victory Capital Management
20
Victory Capital Management
Texas
$114M +$44.9M +150,296 +61%
Fuller & Thaler Asset Management
21
Fuller & Thaler Asset Management
California
$111M -$31.1M -104,081 -21%
Amundi
22
Amundi
France
$107M +$3.78M +12,633 +4%
Bank of New York Mellon
23
Bank of New York Mellon
New York
$104M -$11.3M -37,736 -9%
Arrowstreet Capital
24
Arrowstreet Capital
Massachusetts
$97.4M -$17.7M -59,138 -15%
Charles Schwab
25
Charles Schwab
California
$96.5M -$4.47M -14,973 -4%

UTHR Hedge Fund Activity: Q2 2025 in Review

670 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in United Therapeutics (UTHR) for Q2 2025, worth a combined $12.6B — down 8.8% from $13.9B a quarter earlier.

Buyers outnumbered sellers: 77 funds opened new UTHR positions and 71 closed out — a net gain of 6 holders — while 284 added to existing stakes and 218 trimmed.

The largest buyer was Invesco, adding an estimated $125M. The largest seller was Fidelity Investments, cutting an estimated $215M.

  • 670 institutional investors held United Therapeutics (UTHR) as of Q2 2025, down from 671 in Q1 2025.
  • Funds reported $12.6B of United Therapeutics stock for Q2 2025, down 8.8% quarter-over-quarter.
  • 77 funds opened new United Therapeutics positions in Q2 2025 and 71 closed out, a net change of +6 holders.
  • The largest United Therapeutics buyer in Q2 2025 was Invesco, an estimated $125M added.
  • The largest United Therapeutics seller in Q2 2025 was Fidelity Investments, an estimated $215M sold.

Based on aggregated 13F filings for Q2 2025.