|
1
|
|
$106M
|
–
|
–
|
–
|
|
|
2
|
Paradigm Biocapital Advisors
New York
|
$105M
|
+$5.59M
|
+257,564
|
+6%
|
|
|
3
|
|
$60.9M
|
+$428K
|
+19,723
|
+0.8%
|
|
|
4
|
|
$60M
|
+$747K
|
+34,455
|
+1%
|
|
|
5
|
Jefferies Financial Group
New York
|
$51.5M
|
–
|
–
|
–
|
|
|
6
|
Silverarc Capital Management
Boston,
Massachusetts
|
$40.7M
|
+$3.5M
|
+161,538
|
+10%
|
|
|
7
|
Acorn Capital Advisors
New York
|
$33.9M
|
+$4.09M
|
+188,671
|
+15%
|
|
|
8
|
SG Americas Securities
New York
|
$32.3M
|
+$4.78M
|
+220,264
|
+19%
|
|
|
9
|
American Century Companies
Kansas City,
Missouri
|
$31.8M
|
+$29.5M
|
+1,358,812
|
New
|
|
|
10
|
Menora Mivtachim Holdings
Ramat Gan,
Israel
|
$27M
|
–
|
–
|
–
|
|
|
11
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$26.3M
|
+$24.4M
|
+1,125,100
|
New
|
|
|
12
|
|
$22.5M
|
+$1.6M
|
+73,691
|
+8%
|
|
|
13
|
MPM BioImpact
Boston,
Massachusetts
|
$22M
|
+$17.5M
|
+806,378
|
+597%
|
|
|
14
|
|
$20.5M
|
+$4.05M
|
+186,487
|
+27%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$18.9M
|
-$261K
|
-12,025
|
-1%
|
|
|
16
|
Frontier Capital Management
Boston,
Massachusetts
|
$18.3M
|
+$17M
|
+781,620
|
New
|
|
|
17
|
Migdal Insurance & Financial Holdings
Petach Tikva,
Israel
|
$18.1M
|
–
|
–
|
–
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$17.3M
|
+$2.94M
|
+135,480
|
+22%
|
|
|
19
|
Superstring Capital Management
New York
|
$16.8M
|
+$13.7M
|
+630,442
|
+717%
|
|
|
20
|
TCG Crossover Management
Palo Alto,
California
|
$16.8M
|
–
|
–
|
–
|
|
|
21
|
Millennium Management
New York
|
$14.5M
|
-$18.4M
|
-849,785
|
-58%
|
|
|
22
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$14.4M
|
+$5.64M
|
+259,991
|
+73%
|
|
|
23
|
|
$12M
|
+$11.1M
|
+513,303
|
New
|
|
|
24
|
Woodline Partners
San Francisco,
California
|
$11.7M
|
+$4.22M
|
+194,355
|
+63%
|
|
|
25
|
Boxer Capital Management
San Diego,
California
|
$11.7M
|
-$1.63M
|
-75,000
|
-13%
|
|
