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UroGen Pharma

172 hedge funds and large institutions have $835M invested in UroGen Pharma in 2026 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 52 increasing their positions, 47 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

32% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 25

11% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $3.83M

11% more repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 47

3% more funds holding

Funds holding: 167172 (+5)

1.97% more ownership

Funds ownership: 93.38%95.36% (+2%)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

18% less capital invested

Capital invested by funds: $1.02B → $835M (-$189M)

Holders
172
Holders Change
+5
Holders Change %
+2.99%
% of All Funds
2.12%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
52
Reduced
47
Closed
25
Calls
$4.26M
Puts
$3.83M
Net Calls
+$423K
Net Calls Change
-$26.3M
Name Holding Trade Value Shares
Change
Change in
Stake
RI
1
RTW Investments
New York
$81.7M
BlackRock
2
BlackRock
New York
$51.2M +$4.9M +244,558 +9%
Toronto Dominion Bank
3
Toronto Dominion Bank
Ontario, Canada
$47M +$52.5M +2,616,714 New
Morgan Stanley
4
Morgan Stanley
New York
$46M -$57.4K -2,863 -0.1%
KCM
5
Kynam Capital Management
New Jersey
$40.4M +$45.1M +2,247,393 New
JFG
6
Jefferies Financial Group
New York
$39.5M
PBA
7
Paradigm Biocapital Advisors
New York
$30.6M -$55.5M -2,769,699 -62%
ACA
8
Acorn Capital Advisors
New York
$30.1M +$4.51M +225,000 +16%
SG Americas Securities
9
SG Americas Securities
New York
$29.8M +$5.62M +280,199 +20%
American Century Companies
10
American Century Companies
Missouri
$29.4M +$5.59M +278,758 +21%
SCM
11
Silverarc Capital Management
Massachusetts
$27M -$4.73M -235,776 -14%
OM
12
Opaleye Management
Massachusetts
$25.7M +$23.3M +1,161,577 +433%
FCM
13
Frontier Capital Management
Massachusetts
$23.6M +$10.7M +532,492 +68%
MMH
14
Menora Mivtachim Holdings
Israel
$20.7M
D.E. Shaw & Co
15
D.E. Shaw & Co
New York
$18.4M +$1.21M +60,535 +6%
MB
16
MPM BioImpact
Massachusetts
$17M +$48.6K +2,425 +0.3%
JGC
17
J. Goldman & Co
New York
$16.9M +$8.53M +425,567 +83%
O
18
OrbiMed
New York
$15.7M
State Street
19
State Street
Massachusetts
$15.7M +$1.34M +66,755 +8%
MIFH
20
Migdal Insurance & Financial Holdings
Israel
$13.9M
SCM
21
Soleus Capital Management
Connecticut
$13.1M +$11.6M +577,000 +385%
Goldman Sachs
22
Goldman Sachs
New York
$10.8M +$2.78M +138,806 +30%
Geode Capital Management
23
Geode Capital Management
Massachusetts
$9.42M +$975K +48,619 +10%
WP
24
Woodline Partners
California
$9M
BCM
25
Boxer Capital Management
California
$8.99M

URGN Hedge Fund Activity: Q1 2026 in Review

172 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in UroGen Pharma (URGN) for Q1 2026, worth a combined $835M — down 18% from $1.02B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new URGN positions and 25 closed out — a net gain of 8 holders — while 52 added to existing stakes and 47 trimmed.

The largest buyer was Toronto Dominion Bank, opening a new position worth an estimated $52.5M. The largest seller was Paradigm Biocapital Advisors, cutting an estimated $55.5M.

  • 172 institutional investors held UroGen Pharma (URGN) as of Q1 2026, up from 167 in Q4 2025.
  • Funds reported $835M of UroGen Pharma stock for Q1 2026, down 18% quarter-over-quarter.
  • 33 funds opened new UroGen Pharma positions in Q1 2026 and 25 closed out, a net change of +8 holders.
  • The largest UroGen Pharma buyer in Q1 2026 was Toronto Dominion Bank, an estimated $52.5M added.
  • The largest UroGen Pharma seller in Q1 2026 was Paradigm Biocapital Advisors, an estimated $55.5M sold.

Based on aggregated 13F filings for Q1 2026.