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Taysha Gene Therapies
TSHA

Overview Fund Activity

125 hedge funds and large institutions have $232M invested in Taysha Gene Therapies in 2025 Q1 according to their latest regulatory filings, with 22 funds opening new positions, 38 increasing their positions, 31 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
125
Holders Change
-4
Holders Change %
-3.1%
% of All Funds
1.7%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
22
Increased
38
Reduced
31
Closed
25
Calls
$144K
Puts
$7K
Net Calls
+$137K
Net Calls Change
-$32K

Top Buyers

1
RI
RTW Investments
New York
+$14.1M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
+$6.35M
3
Millennium Management
Millennium Management
New York
+$2.25M
4
ACM
ADAR1 Capital Management
Texas
+$1.24M
5
SCM
Superstring Capital Management
New York
+$1.05M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$8.65M
2
VA
VR Adviser
New York
-$5.58M
3
State Street
State Street
Massachusetts
-$4.5M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$2.28M
5
ACP
Acuta Capital Partners
California
-$1.53M
Name Holding Trade Value Shares
Change 		Shares
Change %
VA
126
VR Adviser
New York
– -$5.58M -3,225,180 Closed
Norges Bank
127
Norges Bank
Norway
– -$2.53M -1,461,120 Closed
ACP
128
Acuta Capital Partners
California
– -$1.53M -884,244 Closed
Renaissance Technologies
129
Renaissance Technologies
New York
– -$1.52M -878,448 Closed
Rafferty Asset Management
130
Rafferty Asset Management
New York
– -$436K -252,257 Closed
Squarepoint
131
Squarepoint
New York
– -$366K -211,842 Closed
Jane Street
132
Jane Street
New York
– -$293K -169,575 Closed
Marshall Wace
133
Marshall Wace
United Kingdom
– -$239K -138,111 Closed
VF
134
Virtu Financial
New York
– -$186K -107,544 Closed
ACM
135
Aquatic Capital Management
Illinois
– -$135K -78,246 Closed
LPL Financial
136
LPL Financial
California
– -$104K -60,000 Closed
PA
137
Profund Advisors
Maryland
– -$86.9K -50,242 Closed
EGM
138
Engineers Gate Manager
New York
– -$61.9K -35,808 Closed
Verition Fund Management
139
Verition Fund Management
Connecticut
– -$59K -34,098 Closed
VEA
140
Virtus ETF Advisers
New York
– -$54.7K -31,597 Closed
SG Americas Securities
141
SG Americas Securities
New York
– -$49K -28,498 Closed
AC
142
AXQ Capital
New Jersey
– -$38.8K -22,432 Closed
EFM
143
E Fund Management
China
– -$30.9K -17,844 Closed
GSC
144
Ground Swell Capital
South Carolina
– -$25.4K -14,660 Closed
Two Sigma Investments
145
Two Sigma Investments
New York
– -$21.3K -12,300 Closed
BIG
146
Brooklyn Investment Group
New York
– -$7.79K -4,500 Closed
RS
147
R Squared
Hong Kong
– -$225 -130 Closed
RIL
148
Rothschild Investment LLC
Illinois
– -$225 -130 Closed
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