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Taysha Gene Therapies
TSHA

Overview Fund Activity

148 hedge funds and large institutions have $595M invested in Taysha Gene Therapies in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 48 increasing their positions, 33 reducing their positions, and 20 closing their positions.

Holders
148
Holders Change
+23
Holders Change %
+18.4%
% of All Funds
1.99%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
44
Increased
48
Reduced
33
Closed
20
Calls
$465K
Puts
$47K
Net Calls
+$418K
Net Calls Change
+$281K

Top Buyers

1
RCM
1
RA Capital Management
Massachusetts
$54.4M
2
Goldman Sachs
2
Goldman Sachs
New York
$29.1M
3
JFG
3
Jefferies Financial Group
New York
$23.8M
4
RI
4
RTW Investments
New York
$57.8M
5
DM
5
Deerfield Management
New York
$12.4M

Top Sellers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$514K
2
GIM
2
Granahan Investment Management
Massachusetts
$2.21M
3
SCM
3
Superstring Capital Management
New York
$0
4
DCM
4
DAFNA Capital Management
California
$0
5
BlackRock
5
BlackRock
New York
$30.7M
Name Market Value Shares Shares
Change 		Shares
Change %
BGI
26
B Group Inc
Texas
$4.16M 1,800,556 +545,000 +43%
GPP
27
Great Point Partners
Connecticut
$3.47M 1,500,000 +1,500,000 New
Northern Trust
28
Northern Trust
Illinois
$3.07M 1,328,741 -102,925 -7%
PAI
29
Palo Alto Investors
California
$2.88M 1,246,033 -173,435 -12%
SC
30
Stempoint Capital
New York
$2.78M 1,203,941 +1,203,941 New
WP
31
Woodline Partners
California
$2.31M 1,000,254 +142,000 +17%
GIM
32
Granahan Investment Management
Massachusetts
$2.21M 958,493 -682,300 -42%
TCM
33
Tang Capital Management
California
$2.08M 900,000 +900,000 New
QPW
34
Quantum Private Wealth
Florida
$1.88M 815,976 +24,500 +3%
AFM
35
Anson Funds Management
Texas
$1.86M 803,500 +803,500 New
Bank of America
36
Bank of America
North Carolina
$1.69M 730,728 +93,886 +15%
SCV
37
Sands Capital Ventures
Virginia
$1.67M 724,873 – –
AI
38
Alphabet Inc
California
$1.48M 640,882 – –
Wellington Management Group
39
Wellington Management Group
Massachusetts
$1.47M 635,968 +10,770 +2%
Citadel Advisors
40
Citadel Advisors
Florida
$1.22M 528,993 +312,382 +144%
Royal Bank of Canada
41
Royal Bank of Canada
Ontario, Canada
$1.15M 495,311 +493,849 +33,779%
SG Americas Securities
42
SG Americas Securities
New York
$1.14M 493,301 +493,301 New
Charles Schwab
43
Charles Schwab
California
$1.14M 491,709 -55,419 -10%
ACP
44
Acuta Capital Partners
California
$1.12M 485,669 +485,669 New
NL
45
Nuveen LLC
North Carolina
$1.07M 465,144 -81,270 -15%
Bank of New York Mellon
46
Bank of New York Mellon
New York
$1.06M 458,659 +5,239 +1%
Barclays
47
Barclays
United Kingdom
$1.04M 450,501 -258,465 -36%
SFM
48
Sphera Funds Management
Israel
$970K 420,000 +420,000 New
D.E. Shaw & Co
49
D.E. Shaw & Co
New York
$927K 401,509 +401,509 New
XT
50
XTX Topco
Cayman Islands
$741K 320,737 +117,608 +58%
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