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Tenaya Therapeutics
TNYA

103 hedge funds and large institutions have $37.5M invested in Tenaya Therapeutics in 2026 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 32 increasing their positions, 18 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

750% more call options, than puts

Call options by funds: $408K | Put options by funds: $48K

78% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 18

37% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 19

6% more funds holding

Funds holding: 97 → 103 (+6)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

16.2% less ownership

Funds ownership: 41.22% → 25.03% (-16%)

23% less capital invested

Capital invested by funds: $48.8M → $37.5M (-$11.3M)

Holders
103
Holders Change
+6
Holders Change %
+6.19%
% of All Funds
1.27%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
26
Increased
32
Reduced
18
Closed
19
Calls
$408K
Puts
$48K
Net Calls
+$360K
Net Calls Change
-$13K

Top Buyers

Rank Fund Capital Flow
1
Renaissance Technologies
Renaissance Technologies
New York
+$1.37M
2
Marshall Wace
Marshall Wace
United Kingdom
+$959K
3
Millennium Management
Millennium Management
New York
+$621K
4
Jane Street
Jane Street
New York
+$370K
5
Geode Capital Management
Geode Capital Management
Massachusetts
+$271K

Top Sellers

Rank Fund Capital Flow
1
CG
Column Group
California
-$6.69M
2
AFM
Anson Funds Management
Texas
-$2.95M
3
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$2.85M
4
SFM
Sphera Funds Management
Israel
-$1.07M
5
EAM
Empery Asset Management
New York
-$832K
Name Holding Trade Value Shares
Change 		Change in
Stake
RSF
76
Rik Saylor Financial
Ohio
$9.35K +$9.96K +13,500 New
AWM
77
Avior Wealth Management
Nebraska
$9.07K +$9.67K +13,100 New
ACA
78
Aptus Capital Advisors
Alabama
$8.35K – – –
LPL Financial
79
LPL Financial
California
$7.93K -$2.49K -3,370 -23%
Mirae Asset Global Investments
80
Mirae Asset Global Investments
South Korea
$7.83K +$2.37K +3,215 +40%
RS
81
R Squared
Hong Kong
$7.76K +$8.27K +11,208 New
GGS
82
Galvin Gaustad & Stein
Arizona
$7.62K – – –
Barclays
83
Barclays
United Kingdom
$7.46K -$129K -174,224 -94%
SFA
84
Sequoia Financial Advisors
Ohio
$7.43K – – –
JRP
85
Jasper Ridge Partners
California
$7.1K – – –
QWM
86
Quadcap Wealth Management
Texas
$6.92K – – –
SPIA
87
Steward Partners Investment Advisory
New York
$5.23K +$5.58K +7,558 New
IA
88
IFP Advisors
Florida
$4.14K +$4.4K +5,962 +37,263%
BNP Paribas Financial Markets
89
BNP Paribas Financial Markets
France
$3.46K -$5.43K -7,354 -60%
Royal Bank of Canada
90
Royal Bank of Canada
Ontario, Canada
$3K +$987 +1,338 +36%
TFM
91
TFC Financial Management
Massachusetts
$1.73K – – –
Fidelity Investments
92
Fidelity Investments
Massachusetts
$1.6K -$337 -456 -16%
Nisa Investment Advisors
93
Nisa Investment Advisors
Missouri
$1.56K – – –
Wells Fargo
94
Wells Fargo
California
$1.38K -$1.48K -2,000 -50%
TFA
95
Toth Financial Advisory
Virginia
$1.04K +$1.11K +1,500 New
VWM
96
Vermillion Wealth Management
Minnesota
$1.04K +$1.11K +1,500 New
EWA
97
EverSource Wealth Advisors
Alabama
$761 -$326 -442 -29%
FFA
98
Farther Finance Advisors
California
$681 – – –
TRCT
99
Tower Research Capital (TRC)
New York
$566 +$603 +817 New
SS
100
SBI Securities
Japan
$542 – – –
1 2 3
4
5

TNYA Hedge Fund Activity: Q1 2026 in Review

103 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Tenaya Therapeutics (TNYA) for Q1 2026, worth a combined $37.5M — down 23% from $48.8M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new TNYA positions and 19 closed out — a net gain of 7 holders — while 32 added to existing stakes and 18 trimmed.

The largest buyer was Renaissance Technologies, adding an estimated $1.37M. The largest seller was Column Group, exiting entirely with an estimated $6.69M sold.

  • 103 institutional investors held Tenaya Therapeutics (TNYA) as of Q1 2026, up from 97 in Q4 2025.
  • Funds reported $37.5M of Tenaya Therapeutics stock for Q1 2026, down 23% quarter-over-quarter.
  • 26 funds opened new Tenaya Therapeutics positions in Q1 2026 and 19 closed out, a net change of +7 holders.
  • The largest Tenaya Therapeutics buyer in Q1 2026 was Renaissance Technologies, an estimated $1.37M added.
  • The largest Tenaya Therapeutics seller in Q1 2026 was Column Group, an estimated $6.69M sold.

Based on aggregated 13F filings for Q1 2026.