|
1
|
|
$278M
|
+$164M
|
+11,809,392
|
+792%
|
|
|
2
|
Adage Capital Partners
Boston,
Massachusetts
|
$268M
|
+$30.6M
|
+2,201,561
|
+21%
|
|
|
3
|
Boxer Capital Management
San Diego,
California
|
$228M
|
–
|
–
|
–
|
|
|
4
|
TCG Crossover Management
Palo Alto,
California
|
$220M
|
-$31.1M
|
-2,231,023
|
-17%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$207M
|
+$98M
|
+7,038,371
|
+245%
|
|
|
6
|
Farallon Capital Management
San Francisco,
California
|
$190M
|
-$55.2M
|
-3,964,000
|
-30%
|
|
|
7
|
|
$183M
|
+$2.88M
|
+207,248
|
+2%
|
|
|
8
|
Woodline Partners
San Francisco,
California
|
$167M
|
-$28.8M
|
-2,072,212
|
-21%
|
|
|
9
|
Nextech Invest
Zurich,
Switzerland
|
$152M
|
–
|
–
|
–
|
|
|
10
|
TRV GP IV
Boston,
Massachusetts
|
$133M
|
-$20.9M
|
-1,500,000
|
-19%
|
|
|
11
|
Siren LLC
Greenwich,
Connecticut
|
$118M
|
-$34.9M
|
-2,508,269
|
-31%
|
|
|
12
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$108M
|
+$71.8M
|
+5,161,431
|
New
|
|
|
13
|
|
$106M
|
+$1.86M
|
+133,978
|
+3%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$97.3M
|
-$21.8M
|
-1,566,673
|
-25%
|
|
|
15
|
Deerfield Management
New York
|
$86.8M
|
+$17.3M
|
+1,239,867
|
+43%
|
|
|
16
|
Paradigm Biocapital Advisors
New York
|
$83.9M
|
+$55.8M
|
+4,009,679
|
New
|
|
|
17
|
Holocene Advisors
New York
|
$82.3M
|
+$54.7M
|
+3,932,603
|
New
|
|
|
18
|
Balyasny Asset Management
Chicago,
Illinois
|
$80.1M
|
-$20.2M
|
-1,451,921
|
-28%
|
|
|
19
|
Logos Global Management
San Francisco,
California
|
$62.8M
|
-$16.7M
|
-1,200,000
|
-29%
|
|
|
20
|
Deep Track Capital
Greenwich,
Connecticut
|
$57.5M
|
+$4.11M
|
+295,438
|
+12%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$56M
|
+$1.7M
|
+122,121
|
+5%
|
|
|
22
|
Caligan Partners
New York
|
$50.4M
|
-$18.4M
|
-1,321,097
|
-35%
|
|
|
23
|
Bellevue Group
Kuesnacht,
Switzerland
|
$50.2M
|
-$21.3M
|
-1,527,670
|
-39%
|
|
|
24
|
Janus Henderson Group
London,
|
$50.1M
|
-$3.47M
|
-249,265
|
-9%
|
|
|
25
|
Vivo Capital
Palo Alto,
California
|
$45.1M
|
–
|
–
|
–
|
|
