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Tango Therapeutics

115 hedge funds and large institutions have $652M invested in Tango Therapeutics in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 30 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,265% more call options, than puts

Call options by funds: $1.32M | Put options by funds: $97K

342% more capital invested

Capital invested by funds: $147M → $652M (+$504M)

75% more funds holding in top 10

Funds holding in top 10: 47 (+3)

40% more repeat investments, than reductions

Existing positions increased: 42 | Existing positions reduced: 30

18.15% more ownership

Funds ownership: 99.24%117.39% (+18%)

6% less funds holding

Funds holding: 122115 (-7)

25% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 28

Holders
115
Holders Change
-7
Holders Change %
-5.74%
% of All Funds
1.51%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.09%
New
21
Increased
42
Reduced
30
Closed
28
Calls
$1.32M
Puts
$97K
Net Calls
+$1.23M
Net Calls Change
+$1.23M
Name Holding Trade Value Shares
Change
Change in
Stake
EWA
76
EverSource Wealth Advisors
Alabama
$136K +$65.8K +26,605 +102,327%
Two Sigma Investments
77
Two Sigma Investments
New York
$114K -$75.9K -30,684 -58%
CUAMC
78
China Universal Asset Management Company
China
$111K +$213 +86 +0.4%
VOYA Investment Management
79
VOYA Investment Management
Georgia
$109K +$17.1K +6,897 +48%
VPIM
80
Vanguard Personalized Indexing Management
California
$104K +$24.1K +9,737 +92%
ProShare Advisors
81
ProShare Advisors
Maryland
$101K +$11.3K +4,570 +30%
VIA
82
Virtus Investment Advisers
Connecticut
$95.3K -$96.4K -38,979 -68%
PFSRSONJ
83
Police & Firemen's Retirement System of New Jersey
New Jersey
$90.4K +$20.8K +8,429 +91%
State Board of Administration of Florida Retirement System
84
State Board of Administration of Florida Retirement System
Florida
$65.4K
Belvedere Trading
85
Belvedere Trading
Illinois
$57.5K +$27.8K +11,231 New
Los Angeles Capital Management
86
Los Angeles Capital Management
California
$52.7K -$294K -118,820 -92%
NFC
87
Northeast Financial Consultants
Connecticut
$51.2K +$24.7K +10,000 New
TRCT
88
Tower Research Capital (TRC)
New York
$48.5K +$7.19K +2,907 +44%
BNP Paribas Financial Markets
89
BNP Paribas Financial Markets
France
$44.1K -$96.2K -38,920 -82%
AIP
90
Ameritas Investment Partners
Nebraska
$40.1K +$8.54K +3,452 +79%
Legal & General Group
91
Legal & General Group
United Kingdom
$35.8K +$4.05K +1,640 +31%
New York State Common Retirement Fund
92
New York State Common Retirement Fund
New York
$33.7K
US Bancorp
93
US Bancorp
Minnesota
$31.7K -$1.51K -611 -9%
Fidelity Investments
94
Fidelity Investments
Massachusetts
$28.6K -$12.8K -5,164 -48%
Carson Wealth (CWM LLC)
95
Carson Wealth (CWM LLC)
Nebraska
$25K +$7.83K +3,167 +182%
California State Teachers Retirement System (CalSTRS)
96
California State Teachers Retirement System (CalSTRS)
California
$24.5K +$3.28K +1,328 +38%
Mirae Asset Global Investments
97
Mirae Asset Global Investments
South Korea
$21.4K +$1.12K +454 +12%
GFM
98
GF Fund Management
China
$13.6K
SCM
99
Sterling Capital Management
North Carolina
$10.6K +$5K +2,022 +4,127%
AB
100
Amalgamated Bank
New York
$8K

TNGX Hedge Fund Activity: Q2 2025 in Review

115 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Tango Therapeutics (TNGX) for Q2 2025, worth a combined $652M — up 342% from $147M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of TNGX and 21 opened new positions — a net loss of 7 holders — while 30 trimmed existing stakes and 42 added.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $14.6M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $3.23M.

  • 115 institutional investors held Tango Therapeutics (TNGX) as of Q2 2025, down from 122 in Q1 2025.
  • Funds reported $652M of Tango Therapeutics stock for Q2 2025, up 342% quarter-over-quarter.
  • 21 funds opened new Tango Therapeutics positions in Q2 2025 and 28 closed out, a net change of -7 holders.
  • The largest Tango Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $14.6M added.
  • The largest Tango Therapeutics seller in Q2 2025 was Blue Owl Capital Holdings, an estimated $3.23M sold.

Based on aggregated 13F filings for Q2 2025.