|
1
|
Opaleye Management
Boston,
Massachusetts
|
$5.3M
|
-$1.14M
|
-388,332
|
-14%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$3.95M
|
+$5.56M
|
+1,900,000
|
New
|
|
|
3
|
Stempoint Capital
New York
|
$2.05M
|
+$2.38M
|
+815,671
|
+484%
|
|
|
4
|
Boxer Capital
San Diego,
California
|
$1.69M
|
+$1.76M
|
+602,400
|
+288%
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$1.38M
|
+$1.87M
|
+639,424
|
+2,464%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$1.12M
|
+$986K
|
+337,161
|
+169%
|
|
|
7
|
Armistice Capital
New York
|
$1.08M
|
+$1.52M
|
+520,000
|
New
|
|
|
8
|
Velan Capital Investment Management
Alpharetta,
Georgia
|
$998K
|
+$1.4M
|
+480,000
|
New
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$889K
|
–
|
–
|
–
|
|
|
10
|
CVI Holdings
Wilmington,
Delaware
|
$630K
|
+$885K
|
+302,746
|
New
|
|
|
11
|
Ikarian Capital
Dallas,
Texas
|
$376K
|
-$64.3K
|
-21,989
|
-11%
|
|
|
12
|
Two Sigma Investments
New York
|
$324K
|
+$398K
|
+136,025
|
+689%
|
|
|
13
|
Renaissance Technologies
New York
|
$313K
|
+$192K
|
+65,800
|
+78%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$292K
|
+$168K
|
+57,619
|
+69%
|
|
|
15
|
Oppenheimer & Co
New York
|
$265K
|
+$343K
|
+117,181
|
+1,172%
|
|
|
16
|
|
$240K
|
+$247K
|
+84,409
|
+273%
|
|
|
17
|
Privium Fund Management (UK)
London,
United Kingdom
|
$233K
|
-$14.7K
|
-5,022
|
-4%
|
|
|
18
|
Woodline Partners
San Francisco,
California
|
$208K
|
+$292K
|
+100,001
|
New
|
|
|
19
|
Two Sigma Advisers
New York
|
$167K
|
+$156K
|
+53,500
|
+198%
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$161K
|
+$226K
|
+77,351
|
New
|
|
|
21
|
LPL Financial
San Diego,
California
|
$91.5K
|
+$46.8K
|
+16,000
|
+57%
|
|
|
22
|
CIBC World Market
Toronto,
Ontario, Canada
|
$77K
|
+$108K
|
+37,000
|
New
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$60.3K
|
+$33.3K
|
+11,385
|
+65%
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$55.3K
|
–
|
–
|
–
|
|
|
25
|
Bridgeway Capital Management
Houston,
Texas
|
$50.3K
|
-$102K
|
-34,800
|
-59%
|
|
