Two Sigma Investments
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Two Sigma Investments’s Protara Therapeutics TARA Stock Holding History

Two Sigma Investments’s Portfolio TARA Stock Details TARA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$197K Buy
37,838
+5,176
+16% +$30.6K ﹤0.01% 4284
2025
Q4 		$174K Buy
32,662
+13,104
+67% +$72.9K ﹤0.01% 3784
2025
Q3 		$85.1K Buy
19,558
+5,154
+36% +$16.7K ﹤0.01% 3489
2025
Q2 		$43.6K Sell
14,404
-9,186
-39% -$31.7K ﹤0.01% 3077
2025
Q1 		$100K Buy
23,590
+9,957
+73% +$44.5K ﹤0.01% 2964
2024
Q4 		$72K Sell
13,633
-171,590
-93% -$554K ﹤0.01% 3008
2024
Q3 		$339K Buy
185,223
+29,450
+19% +$60.5K ﹤0.01% 2629
2024
Q2 		$324K Buy
155,773
+136,025
+689% +$398K ﹤0.01% 2563
2024
Q1 		$79.2K Sell
19,748
-5,397
-21% -$17.4K ﹤0.01% 2852
2023
Q4 		$47.1K Sell
25,145
-2,200
-8% -$3.24K ﹤0.01% 3000
2023
Q3 		$45.7K Sell
27,345
-7,400
-21% -$17K ﹤0.01% 2827
2023
Q2 		$83K Sell
34,745
-1,000
-3% -$2.97K ﹤0.01% 2775
2023
Q1 		$112K Sell
35,745
-10,402
-23% -$34.4K ﹤0.01% 2659
2022
Q4 		$124K Sell
46,147
-4,901
-10% -$15.5K ﹤0.01% 2481
2022
Q3 		$151K Sell
51,048
-2,500
-5% -$8.47K ﹤0.01% 2165
2022
Q2 		$157K Sell
53,548
-35,231
-40% -$129K ﹤0.01% 2212
2022
Q1 		$454K Sell
88,779
-101,499
-53% -$534K ﹤0.01% 2068
2021
Q4 		$1.28M Buy
190,278
+59,343
+45% +$409K ﹤0.01% 2332
2021
Q3 		$906K Buy
130,935
+75,530
+136% +$589K ﹤0.01% 2698
2021
Q2 		$540K Buy
+55,405
New +$628K ﹤0.01% 3028
2021
Q1 		– Sell
-28,599
Closed -$692K – 4236
2020
Q4 		$692K Buy
28,599
+18,480
+183% +$398K ﹤0.01% 2272
2020
Q3 		$170K Buy
+10,119
New +$235K ﹤0.01% 2856

Other funds holding TARA

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCIM
Velan Capital Investment Management Alpharetta, Georgia $160M AUM 517.12% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
Blackstone Inc
Blackstone Inc New York $25.6B AUM 26.83% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
SCM
Sio Capital Management New York $697M AUM 79.73% 1-Year Est. Return
ACA
Acorn Capital Advisors New York $352M AUM 299.18% 1-Year Est. Return
IHAM
Integral Health Asset Management New York $2.09B AUM 112.84% 1-Year Est. Return
ACM
AIGH Capital Management Baltimore, Maryland $733M AUM 327.32% 1-Year Est. Return

Two Sigma Investments's TARA Position: Q1 2026 in Review

Two Sigma Investments increased its Protara Therapeutics (TARA) stake by 16% in Q1 2026, buying an estimated $30.6K and bringing the position to 37,838 shares worth $197K. The position accounts for ﹤0.01% of the portfolio, ranked #4284.

Two Sigma Investments first reported a position in TARA in Q3 2020 and has held it in 22 quarters since. The position peaked at $1.28M in Q4 2021. 114 funds tracked by Wall St. Rank hold TARA as of Q1 2026.

  • Two Sigma Investments held 37,838 shares of Protara Therapeutics worth $197K as of Q1 2026.
  • Two Sigma Investments bought 5,176 Protara Therapeutics shares in Q1 2026, an estimated $30.6K.
  • Protara Therapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #4284 holding.
  • Two Sigma Investments first reported a position in Protara Therapeutics in Q3 2020 and has held it in 22 quarters since.
  • Two Sigma Investments's Protara Therapeutics position peaked at $1.28M in Q4 2021.
  • 114 funds tracked by Wall St. Rank held Protara Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.