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Protara Therapeutics

105 hedge funds and large institutions have $212M invested in Protara Therapeutics in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 46 increasing their positions, 15 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

748% more call options, than puts

Call options by funds: $907K | Put options by funds: $107K

357% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 7

207% more repeat investments, than reductions

Existing positions increased: 46 | Existing positions reduced: 15

86% more capital invested

Capital invested by funds: $114M → $212M (+$98.3M)

30% more funds holding

Funds holding: 81105 (+24)

9.19% more ownership

Funds ownership: 67.95%77.14% (+9.2%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

Holders
105
Holders Change
+24
Holders Change %
+29.63%
% of All Funds
1.28%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
32
Increased
46
Reduced
15
Closed
7
Calls
$907K
Puts
$107K
Net Calls
+$800K
Net Calls Change
+$878K
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$27.4M +$5.06M +910,285 +22%
VCIM
2
Velan Capital Investment Management
Georgia
$15.1M +$3.87M +695,652 +33%
BlackRock
3
BlackRock
New York
$12.8M +$998K +179,500 +8%
Vanguard Group
4
Vanguard Group
Pennsylvania
$12.7M +$2.71M +487,747 +26%
IHAM
5
Integral Health Asset Management
New York
$12M +$4.73M +850,000 +61%
Blackstone Inc
6
Blackstone Inc
New York
$10.2M
ACA
7
Acorn Capital Advisors
New York
$9.34M
SCM
8
Sio Capital Management
New York
$9.14M +$9.54M +1,715,394 New
CCM
9
Catalio Capital Management
New York
$7.71M -$303K -54,539 -4%
5VM
10
5AM Venture Management
California
$7.3M +$3.17M +569,782 +71%
DCM
11
Driehaus Capital Management
Illinois
$6.71M +$4.53M +814,983 +183%
UBS Group
12
UBS Group
Switzerland
$6.48M +$2.07M +372,463 +44%
ACM
13
ADAR1 Capital Management
Texas
$6.06M +$6.12M +1,101,576 +3,127%
Adage Capital Partners
14
Adage Capital Partners
Massachusetts
$5.56M +$5.8M +1,043,478 New
BBA
15
Baker Bros. Advisors
New York
$5.18M +$2.42M +434,782 +81%
Citadel Advisors
16
Citadel Advisors
Florida
$4.81M +$2.22M +399,087 +79%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$4.36M +$325K +58,477 +8%
MS
18
Maven Securities
Jersey
$4.02M +$4.2M +754,626 New
Millennium Management
19
Millennium Management
New York
$4.02M +$362K +65,046 +9%
SFM
20
Sphera Funds Management
Israel
$3.46M +$3.61M +650,000 New
Marshall Wace
21
Marshall Wace
United Kingdom
$3.12M +$1.66M +298,942 +105%
State Street
22
State Street
Massachusetts
$3.04M +$1.23M +220,787 +63%
Bank of America
23
Bank of America
North Carolina
$2.64M +$1.75M +315,429 +175%
BGM
24
Burkehill Global Management
New York
$2.4M +$2.5M +450,000 New
SCM
25
Superstring Capital Management
New York
$1.92M

TARA Hedge Fund Activity: Q4 2025 in Review

105 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Protara Therapeutics (TARA) for Q4 2025, worth a combined $212M — up 86% from $114M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new TARA positions and 7 closed out — a net gain of 25 holders — while 46 added to existing stakes and 15 trimmed.

The largest buyer was Sio Capital Management, opening a new position worth an estimated $9.54M. The largest seller was Stempoint Capital, exiting entirely with an estimated $1.58M sold.

  • 105 institutional investors held Protara Therapeutics (TARA) as of Q4 2025, up from 81 in Q3 2025.
  • Funds reported $212M of Protara Therapeutics stock for Q4 2025, up 86% quarter-over-quarter.
  • 32 funds opened new Protara Therapeutics positions in Q4 2025 and 7 closed out, a net change of +25 holders.
  • The largest Protara Therapeutics buyer in Q4 2025 was Sio Capital Management, an estimated $9.54M added.
  • The largest Protara Therapeutics seller in Q4 2025 was Stempoint Capital, an estimated $1.58M sold.

Based on aggregated 13F filings for Q4 2025.