Spyre Therapeutics

SYRE

Market cap $3.38B

Buy

Hold

Sell

4 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target

Avg. target

$59

38% upside

High target

positive

0 neutral

negative

Analyst & Firm	Rating	Price Target	Upside Downside	Date
Wells Fargo Yanan Zhu 100% 1-yr SYRE win rate				20 Feb ‘26 9 days ago
BTIG Julian Harrison 100% 1-yr SYRE win rate				20 Feb ‘26 9 days ago
Mizuho Joseph Catanzaro 100% 1-yr SYRE win rate				18 Dec ‘25 2 months ago
Citigroup Samantha Semenkow 100% 1-yr SYRE win rate				17 Dec ‘25 2 months ago