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Stoke Therapeutics
STOK

196 hedge funds and large institutions have $2.31B invested in Stoke Therapeutics in 2026 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 79 increasing their positions, 52 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 27

52% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 52

9% more capital invested

Capital invested by funds: $2.13B → $2.31B (+$189M)

7% more funds holding

Funds holding: 183 → 196 (+13)

2.94% more ownership

Funds ownership: 117.28% → 120.21% (+2.9%)

0% more funds holding in top 10

Funds holding in top 10: 4 → 4 (0)

57% less call options, than puts

Call options by funds: $3.7M | Put options by funds: $8.68M

Holders
196
Holders Change
+13
Holders Change %
+7.1%
% of All Funds
2.41%
Holding in Top 10
4
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
43
Increased
79
Reduced
52
Closed
27
Calls
$3.7M
Puts
$8.68M
Net Calls
-$4.98M
Net Calls Change
-$22.7M

Top Buyers

1
Wellington Management Group
Wellington Management Group
Massachusetts
+$77.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$51.2M
3
TCA
Troluce Capital Advisors
Puerto Rico
+$21.4M
4
Millennium Management
Millennium Management
New York
+$15.5M
5
Bank of America
Bank of America
North Carolina
+$11M

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$38.8M
2
LCM
Lynx1 Capital Management
Puerto Rico
-$21M
3
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$10.5M
4
Goldman Sachs
Goldman Sachs
New York
-$10.2M
5
SL
Siren LLC
Connecticut
-$8.26M
Name Holding Trade Value Shares
Change 		Change in
Stake
EC
51
EcoR1 Capital
California
$3.26M +$3.28M +100,000 New
PAI
52
Palo Alto Investors
California
$2.76M +$414K +12,609 +18%
HSA
53
Hussman Strategic Advisors
Maryland
$2.74M +$689K +21,000 +33%
RPAM
54
Rhenman & Partners Asset Management
Sweden
$2.7M -$4.36M -133,000 -62%
Swiss National Bank
55
Swiss National Bank
Switzerland
$2.58M +$112K +3,400 +4%
QC
56
Quantedge Capital
Singapore
$2.56M -$282K -8,600 -10%
TD Asset Management
57
TD Asset Management
Ontario, Canada
$2.42M +$2.44M +74,400 New
Manulife (Manufacturers Life Insurance)
58
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.25M +$1.83M +55,672 +411%
RhumbLine Advisers
59
RhumbLine Advisers
Massachusetts
$2.19M +$161K +4,901 +8%
Jane Street
60
Jane Street
New York
$2.1M -$90.6K -2,763 -4%
Principal Financial Group
61
Principal Financial Group
Iowa
$2.08M -$208K -6,349 -9%
HIS
62
Harvest Investment Services
Illinois
$2.05M +$803K +24,491 +64%
HS
63
HighVista Strategies
Massachusetts
$2.04M -$1.74M -52,922 -46%
Rafferty Asset Management
64
Rafferty Asset Management
New York
$1.95M -$994K -30,295 -34%
UBS AM
65
UBS AM
Illinois
$1.89M +$31.9K +973 +2%
Susquehanna International Group
66
Susquehanna International Group
Pennsylvania
$1.87M +$370K +11,269 +24%
BNP Paribas Financial Markets
67
BNP Paribas Financial Markets
France
$1.83M +$1.7M +51,871 +1,218%
EI
68
EAM Investors
California
$1.69M -$2.16M -65,823 -56%
California State Teachers Retirement System (CalSTRS)
69
California State Teachers Retirement System (CalSTRS)
California
$1.68M +$475K +14,479 +39%
WP
70
Woodline Partners
California
$1.63M – – –
PFM
71
Privium Fund Management
Netherlands
$1.63M -$164K -5,000 -9%
D.E. Shaw & Co
72
D.E. Shaw & Co
New York
$1.63M +$2.33K +71 +0.1%
SSA
73
Schonfeld Strategic Advisors
New York
$1.61M -$453K -13,807 -22%
Creative Planning
74
Creative Planning
Kansas
$1.57M +$210K +6,396 +15%
State of Wisconsin Investment Board
75
State of Wisconsin Investment Board
Wisconsin
$1.56M +$1.08M +33,040 +223%
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STOK Hedge Fund Activity: Q1 2026 in Review

196 of the 8,125 institutional investors tracked by Wall St. Rank reported a position in Stoke Therapeutics (STOK) for Q1 2026, worth a combined $2.31B — up 8.9% from $2.13B a quarter earlier.

Buyers outnumbered sellers: 43 funds opened new STOK positions and 27 closed out — a net gain of 16 holders — while 79 added to existing stakes and 52 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $77.4M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $38.8M sold.

  • 196 institutional investors held Stoke Therapeutics (STOK) as of Q1 2026, up from 183 in Q4 2025.
  • Funds reported $2.31B of Stoke Therapeutics stock for Q1 2026, up 8.9% quarter-over-quarter.
  • 43 funds opened new Stoke Therapeutics positions in Q1 2026 and 27 closed out, a net change of +16 holders.
  • The largest Stoke Therapeutics buyer in Q1 2026 was Wellington Management Group, an estimated $77.4M added.
  • The largest Stoke Therapeutics seller in Q1 2026 was Point72 Asset Management, an estimated $38.8M sold.

Based on aggregated 13F filings for Q1 2026.