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Sarepta Therapeutics
SRPT

Overview Fund Activity

357 hedge funds and large institutions have $1.42B invested in Sarepta Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 159 increasing their positions, 86 reducing their positions, and 128 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
357
Holders Change
-69
Holders Change %
-16.2%
% of All Funds
4.79%
Holding in Top 10
–
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-100%
% of All Funds
–
New
64
Increased
159
Reduced
86
Closed
128
Calls
$132M
Puts
$79.5M
Net Calls
+$52.1M
Net Calls Change
+$31M

Top Buyers

1
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$76.5M
2
BlackRock
BlackRock
New York
+$37.8M
3
Two Sigma Advisers
Two Sigma Advisers
New York
+$29.2M
4
Two Sigma Investments
Two Sigma Investments
New York
+$27.5M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$26.8M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$171M
2
FCM
Farallon Capital Management
California
-$149M
3
Capital International Investors
Capital International Investors
California
-$146M
4
EC
EcoR1 Capital
California
-$82.5M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$56.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$207M +$37.8M +2,208,354 +22%
Vanguard Group
2
Vanguard Group
Pennsylvania
$157M +$2.18M +127,566 +1%
State Street
3
State Street
Massachusetts
$80.3M +$10.7M +626,555 +15%
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$76.6M +$76.5M +4,474,232 +101,549%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$43.3M -$1.99M -116,164 -4%
Two Sigma Investments
6
Two Sigma Investments
New York
$37M +$27.5M +1,610,817 +292%
Two Sigma Advisers
7
Two Sigma Advisers
New York
$34M +$29.2M +1,709,400 +619%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$32.1M +$942K +55,076 +3%
EAM
9
Erste Asset Management
Austria
$27.7M +$9.58M +560,350 +53%
Qube Research & Technologies (QRT)
10
Qube Research & Technologies (QRT)
United Kingdom
$27.3M +$26.8M +1,566,564 +4,910%
Morgan Stanley
11
Morgan Stanley
New York
$25.4M -$8.3M -485,196 -25%
Voloridge Investment Management
12
Voloridge Investment Management
Florida
$25.2M +$17.4M +1,016,827 +222%
Federated Hermes
13
Federated Hermes
Pennsylvania
$22.4M +$17.4M +1,016,069 +348%
Aberdeen Group
14
Aberdeen Group
United Kingdom
$21.5M +$10.2M +592,125 +91%
BNP Paribas Financial Markets
15
BNP Paribas Financial Markets
France
$21.1M +$20.5M +1,199,741 +3,528%
Millennium Management
16
Millennium Management
New York
$18.2M +$14.6M +855,260 +413%
CC
17
Casdin Capital
New York
$16.9M +$1.53M +89,314 +10%
Bank of America
18
Bank of America
North Carolina
$15.7M +$3.84M +224,650 +32%
Norges Bank
19
Norges Bank
Norway
$15.6M +$15.6M +913,407 New
YIH
20
Y-Intercept (HK)
Hong Kong
$14.9M +$14.1M +822,799 +1,737%
Assenagon Asset Management
21
Assenagon Asset Management
Luxembourg
$14.8M +$2.66M +155,358 +22%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$13.7M +$3.72M +217,570 +37%
Northern Trust
23
Northern Trust
Illinois
$13M -$176K -10,264 -1%
Jane Street
24
Jane Street
New York
$11.6M +$8.91M +521,225 +336%
6CM
25
683 Capital Management
New York
$11.5M +$8.72M +510,000 +309%
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