Two Sigma Investments
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Two Sigma Investments’s Sarepta Therapeutics SRPT Stock Holding History

Two Sigma Investments’s Portfolio SRPT Stock Details SRPT Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$82.6M Buy
4,598,735
+5,540
+0.1% +$105K 0.06% 368
2026
Q1 		$99.9M Buy
4,593,195
+2,151,740
+88% +$41.6M 0.08% 275
2025
Q4 		$52.5M Buy
2,441,455
+303,691
+14% +$6.4M 0.07% 336
2025
Q3 		$41.2M Sell
2,137,764
-23,933
-1% -$427K 0.06% 374
2025
Q2 		$37M Buy
2,161,697
+1,610,817
+292% +$68.7M 0.07% 360
2025
Q1 		$35.2M Buy
550,880
+475,826
+634% +$50.1M 0.08% 313
2024
Q4 		$9.13M Sell
75,054
-127,216
-63% -$15.6M 0.02% 796
2024
Q3 		$25.3M Sell
202,270
-339,524
-63% -$46.9M 0.06% 410
2024
Q2 		$85.6M Buy
541,794
+199,112
+58% +$25.6M 0.2% 119
2024
Q1 		$44.4M Buy
342,682
+40,342
+13% +$4.94M 0.1% 251
2023
Q4 		$29.2M Sell
302,340
-508,127
-63% -$48.7M 0.07% 329
2023
Q3 		$98.2M Sell
810,467
-478,731
-37% -$54.1M 0.26% 98
2023
Q2 		$148M Buy
1,289,198
+192,055
+18% +$24.8M 0.37% 60
2023
Q1 		$151M Buy
1,097,143
+405,737
+59% +$52.6M 0.43% 51
2022
Q4 		$89.6M Sell
691,406
-98,306
-12% -$11.4M 0.28% 85
2022
Q3 		$87.3M Buy
789,712
+759,045
+2,475% +$76.5M 0.3% 85
2022
Q2 		$2.3M Sell
30,667
-262,632
-90% -$19.3M 0.01% 1125
2022
Q1 		$22.9M Sell
293,299
-512,962
-64% -$39.3M 0.07% 353
2021
Q4 		$72.6M Buy
806,261
+553,885
+219% +$47.4M 0.16% 161
2021
Q3 		$23.3M Buy
252,376
+231,409
+1,104% +$17.8M 0.05% 412
2021
Q2 		$1.63M Sell
20,967
-65,300
-76% -$4.95M ﹤0.01% 2050
2021
Q1 		$6.43M Buy
+86,267
New +$7.96M 0.02% 917
2018
Q2 		– Sell
-56,203
Closed -$4.16M – 3627
2018
Q1 		$4.16M Buy
+56,203
New +$3.75M 0.01% 1061
2017
Q1 		– Sell
-263,229
Closed -$7.22M – 3299
2016
Q4 		$7.22M Buy
+263,229
New +$10.6M 0.03% 665
2016
Q1 		– Sell
-115,518
Closed -$4.46M – 3104
2015
Q4 		$4.46M Buy
115,518
+26,251
+29% +$851K 0.02% 705
2015
Q3 		$2.87M Buy
+89,267
New +$3.03M 0.01% 700

Other funds holding SRPT

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
First Trust Advisors
First Trust Advisors Wheaton, Illinois $170B AUM 46.21% 1-Year Est. Return
AQR Capital Management
AQR Capital Management Greenwich, Connecticut $287B AUM 42.33% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
EAM
Erste Asset Management Vienna, Austria $12.9B AUM 52.69% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $127B AUM 46.06% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

Two Sigma Investments's SRPT Position: Q2 2026 in Review

Two Sigma Investments increased its Sarepta Therapeutics (SRPT) stake by 0.12% in Q2 2026, buying an estimated $105K and bringing the position to 4,598,735 shares worth $82.6M. The position accounts for 0.06% of the portfolio, ranked #368.

Two Sigma Investments first reported a position in SRPT in Q3 2015 and has held it in 26 quarters since. The position peaked at $151M in Q1 2023. 323 funds tracked by Wall St. Rank hold SRPT as of Q2 2026.

  • Two Sigma Investments held 4,598,735 shares of Sarepta Therapeutics worth $82.6M as of Q2 2026.
  • Two Sigma Investments bought 5,540 Sarepta Therapeutics shares in Q2 2026, an estimated $105K.
  • Sarepta Therapeutics made up 0.06% of Two Sigma Investments's portfolio in Q2 2026, its #368 holding.
  • Two Sigma Investments first reported a position in Sarepta Therapeutics in Q3 2015 and has held it in 26 quarters since.
  • Two Sigma Investments's Sarepta Therapeutics position peaked at $151M in Q1 2023.
  • 323 funds tracked by Wall St. Rank held Sarepta Therapeutics as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.