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Sarepta Therapeutics
SRPT

Overview Fund Activity

357 hedge funds and large institutions have $1.42B invested in Sarepta Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 159 increasing their positions, 86 reducing their positions, and 128 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
357
Holders Change
-69
Holders Change %
-16.2%
% of All Funds
4.79%
Holding in Top 10
–
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-100%
% of All Funds
–
New
64
Increased
159
Reduced
86
Closed
128
Calls
$132M
Puts
$79.5M
Net Calls
+$52.1M
Net Calls Change
+$31M

Top Buyers

1
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$76.5M
2
BlackRock
BlackRock
New York
+$37.8M
3
Two Sigma Advisers
Two Sigma Advisers
New York
+$29.2M
4
Two Sigma Investments
Two Sigma Investments
New York
+$27.5M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$26.8M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$171M
2
FCM
Farallon Capital Management
California
-$149M
3
Capital International Investors
Capital International Investors
California
-$146M
4
EC
EcoR1 Capital
California
-$82.5M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$56.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
MB
51
MPM BioImpact
Massachusetts
$5.5M +$5.5M +321,696 New
Citadel Advisors
52
Citadel Advisors
Florida
$5.17M +$1.13M +66,368 +28%
QOP
53
Quinn Opportunity Partners
Virginia
$4.95M +$4.95M +289,722 New
JG
54
Jain Global
New York
$4.83M +$4.83M +282,437 New
TC
55
TwinBeech Capital
New York
$4.79M +$258K +15,100 +6%
Wells Fargo
56
Wells Fargo
California
$4.67M +$2.12M +124,227 +83%
Hudson Bay Capital Management
57
Hudson Bay Capital Management
Connecticut
$4.58M +$1.16M +67,850 +34%
RhumbLine Advisers
58
RhumbLine Advisers
Massachusetts
$4.57M +$35.4K +2,070 +0.8%
DTC
59
Deep Track Capital
Connecticut
$4.44M -$10.9M -639,931 -71%
Jacobs Levy Equity Management
60
Jacobs Levy Equity Management
New Jersey
$4.18M +$4.18M +244,533 New
Invesco
61
Invesco
Georgia
$4.16M +$654K +38,240 +19%
Legal & General Group
62
Legal & General Group
United Kingdom
$4.02M +$454K +26,540 +13%
Franklin Resources
63
Franklin Resources
California
$3.97M -$47.3K -2,765 -1%
Bank of Nova Scotia
64
Bank of Nova Scotia
Ontario, Canada
$3.91M +$3.91M +228,731 New
Principal Financial Group
65
Principal Financial Group
Iowa
$3.83M -$357K -20,880 -9%
ACM
66
Aquatic Capital Management
Illinois
$3.69M +$2.11M +123,501 +134%
Amundi
67
Amundi
France
$3.69M -$4.62M -253,989 -56%
Citigroup
68
Citigroup
New York
$3.6M -$2.97M -173,507 -45%
ACM
69
ADAR1 Capital Management
Texas
$3.6M +$1.49M +87,392 +71%
DFCM
70
Dark Forest Capital Management
Puerto Rico
$3.41M +$3.33M +194,464 +3,903%
Prudential Financial
71
Prudential Financial
New Jersey
$3.13M -$1.78M -18,250 -36%
Susquehanna International Group
72
Susquehanna International Group
Pennsylvania
$3.08M +$2.08M +121,470 +207%
Pictet Asset Management
73
Pictet Asset Management
Switzerland
$3.06M -$13M -758,372 -81%
NL
74
Nuveen LLC
North Carolina
$2.98M -$3.05M -178,456 -51%
Swiss National Bank
75
Swiss National Bank
Switzerland
$2.85M – – –
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