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Sarepta Therapeutics
SRPT

Overview Fund Activity

357 hedge funds and large institutions have $1.42B invested in Sarepta Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 159 increasing their positions, 86 reducing their positions, and 128 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
357
Holders Change
-69
Holders Change %
-16.2%
% of All Funds
4.79%
Holding in Top 10
–
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-100%
% of All Funds
–
New
64
Increased
159
Reduced
86
Closed
128
Calls
$132M
Puts
$79.5M
Net Calls
+$52.1M
Net Calls Change
+$31M

Top Buyers

1
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$76.5M
2
BlackRock
BlackRock
New York
+$37.8M
3
Two Sigma Advisers
Two Sigma Advisers
New York
+$29.2M
4
Two Sigma Investments
Two Sigma Investments
New York
+$27.5M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$26.8M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$171M
2
FCM
Farallon Capital Management
California
-$149M
3
Capital International Investors
Capital International Investors
California
-$146M
4
EC
EcoR1 Capital
California
-$82.5M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$56.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
Charles Schwab
26
Charles Schwab
California
$11.5M +$472K +27,586 +4%
JPMorgan Chase & Co
27
JPMorgan Chase & Co
New York
$11.2M -$27.2M -1,592,233 -71%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$11.1M -$2.42M -141,805 -18%
First Trust Advisors
29
First Trust Advisors
Illinois
$10.7M +$3.99M +233,391 +59%
Renaissance Technologies
30
Renaissance Technologies
New York
$10.7M +$10.7M +624,478 New
Connor, Clark & Lunn Investment Management (CC&L)
31
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$10.5M +$6.34M +370,672 +151%
JF
32
Jump Financial
Illinois
$10.3M +$10.2M +597,484 +10,328%
Capital Fund Management (CFM)
33
Capital Fund Management (CFM)
France
$8.8M +$5.38M +314,608 +157%
UBS Group
34
UBS Group
Switzerland
$8.57M -$16.2M -945,374 -65%
OM
35
Opaleye Management
Massachusetts
$8.55M +$8.55M +500,000 New
Capital International Investors
36
Capital International Investors
California
$8.52M -$146M -8,562,435 -95%
CWG
37
C WorldWide Group
Denmark
$8.39M +$4.1M +240,000 +96%
Royal Bank of Canada
38
Royal Bank of Canada
Ontario, Canada
$8.36M -$936K -54,707 -10%
T. Rowe Price Investment Management
39
T. Rowe Price Investment Management
Maryland
$8.12M -$26M -1,523,233 -76%
Ameriprise
40
Ameriprise
Minnesota
$7.88M +$2.12M +124,211 +37%
IC
41
Ikarian Capital
Texas
$7.68M +$4.79M +280,000 +166%
Balyasny Asset Management
42
Balyasny Asset Management
Illinois
$7.6M +$7.6M +444,728 New
Walleye Capital
43
Walleye Capital
New York
$7.46M +$7.24M +423,278 +3,269%
TCM
44
Tang Capital Management
California
$7.19M +$7.19M +420,300 New
Barclays
45
Barclays
United Kingdom
$7.04M -$584K -34,134 -8%
UBS AM
46
UBS AM
Illinois
$6.77M -$1.15M -67,175 -14%
TI
47
Trexquant Investment
Connecticut
$6.63M +$3.41M +199,513 +106%
Goldman Sachs
48
Goldman Sachs
New York
$6.43M +$3.32M +194,209 +107%
IG
49
ING Group
Netherlands
$6.37M +$6.37M +489,100 New
Fiera Capital (Canada)
50
Fiera Capital (Canada)
Quebec, Canada
$5.88M -$28.6K -1,675 -0.5%
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