|
1
|
Avidity Partners Management
Dallas,
Texas
|
$106M
|
–
|
–
|
–
|
|
|
2
|
|
$80.8M
|
+$3.02M
|
+163,596
|
+5%
|
|
|
3
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$62.4M
|
+$3.57M
|
+193,400
|
+7%
|
|
|
4
|
Frazier Management
Seattle,
Washington
|
$60.7M
|
+$29.3M
|
+1,583,927
|
+133%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$54.3M
|
+$6.96M
|
+376,757
|
+18%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$51.2M
|
+$3.1M
|
+167,964
|
+8%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$47.6M
|
+$11.6M
|
+630,000
|
+41%
|
|
|
8
|
PFM Health Sciences
San Francisco,
California
|
$46M
|
+$4.56M
|
+246,774
|
+13%
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$46M
|
-$7.15M
|
-386,715
|
-16%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$44.2M
|
+$3.24M
|
+175,470
|
+10%
|
|
|
11
|
|
$43.4M
|
+$33.1M
|
+1,790,700
|
+940%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$35M
|
-$1.44M
|
-78,093
|
-5%
|
|
|
13
|
683 Capital Management
New York
|
$30.5M
|
+$4.8M
|
+259,592
|
+23%
|
|
|
14
|
Adage Capital Partners
Boston,
Massachusetts
|
$26.3M
|
-$30.8M
|
-1,666,272
|
-58%
|
|
|
15
|
Sphera Funds Management
Tel Aviv,
Israel
|
$25.8M
|
+$7.87M
|
+425,982
|
+57%
|
|
|
16
|
Eventide Asset Management
Boston,
Massachusetts
|
$25.5M
|
–
|
–
|
–
|
|
|
17
|
HealthCor Management
New York
|
$25.3M
|
-$1.06M
|
-57,110
|
-5%
|
|
|
18
|
Aisling Capital Management
New York
|
$22.4M
|
–
|
–
|
–
|
|
|
19
|
Kynam Capital Management
Princeton,
New Jersey
|
$20.9M
|
+$17.7M
|
+956,165
|
New
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$20.8M
|
+$9.93M
|
+537,385
|
+130%
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$17.4M
|
+$2.69M
|
+145,674
|
+22%
|
|
|
22
|
Barclays
London,
United Kingdom
|
$17M
|
+$6.89M
|
+373,088
|
+93%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$16.7M
|
+$580K
|
+31,407
|
+4%
|
|
|
24
|
Palo Alto Investors
Palo Alto,
California
|
$13.1M
|
+$2.85M
|
+154,000
|
+35%
|
|
|
25
|
|
$10.6M
|
+$8.96M
|
+484,900
|
New
|
|
