|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$23.5M
|
-$1.09M
|
-111,356
|
-3%
|
|
|
2
|
MPM Asset Management
Boston,
Massachusetts
|
$15.2M
|
–
|
–
|
–
|
|
|
3
|
|
$11.7M
|
+$3.87M
|
+394,145
|
+31%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$8.66M
|
-$19.6M
|
-2,000,000
|
-62%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.36M
|
+$186K
|
+18,996
|
+3%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$3.93M
|
–
|
–
|
–
|
|
|
7
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.92M
|
+$1.58M
|
+161,146
|
+41%
|
|
|
8
|
|
$3.07M
|
–
|
–
|
–
|
|
|
9
|
683 Capital Management
New York
|
$2.63M
|
+$900K
|
+91,770
|
+32%
|
|
|
10
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.38M
|
+$106K
|
+10,834
|
+3%
|
|
|
11
|
|
$1.95M
|
-$1.47M
|
-149,779
|
-35%
|
|
|
12
|
|
$1.71M
|
+$32.2K
|
+3,286
|
+1%
|
|
|
13
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.4M
|
–
|
–
|
–
|
|
|
14
|
Stonepine Capital Management
Bend,
Oregon
|
$1.39M
|
+$1.95M
|
+198,373
|
New
|
|
|
15
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$1.26M
|
+$1.77M
|
+180,000
|
New
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$1.23M
|
+$306K
|
+31,146
|
+22%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$1.18M
|
+$136K
|
+13,835
|
+9%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$1.08M
|
+$236K
|
+24,066
|
+19%
|
|
|
19
|
Millennium Management
New York
|
$1.05M
|
-$1.89M
|
-192,378
|
-56%
|
|
|
20
|
Tiverton Asset Management
Wilimington,
Delaware
|
$929K
|
–
|
–
|
–
|
|
|
21
|
United Services Automobile Association
San Antonio,
Texas
|
$889K
|
-$15.1K
|
-1,535
|
-1%
|
|
|
22
|
Boxer Capital
San Diego,
California
|
$702K
|
–
|
–
|
–
|
|
|
23
|
Sofinnova Investments
Menlo Park,
California
|
$693K
|
+$849K
|
+86,489
|
+713%
|
|
|
24
|
Panagora Asset Management
Boston,
Massachusetts
|
$613K
|
+$305K
|
+31,125
|
+55%
|
|
|
25
|
Bank of New York Mellon
New York
|
$564K
|
+$333K
|
+33,892
|
+73%
|
|
