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Syndax Pharmaceuticals

218 hedge funds and large institutions have $1.25B invested in Syndax Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 31 funds opening new positions, 88 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

129% more call options, than puts

Call options by funds: $18.1M | Put options by funds: $7.88M

40% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 63

25% more funds holding in top 10

Funds holding in top 10: 810 (+2)

19% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 26

2.52% more ownership

Funds ownership: 114.85%117.37% (+2.5%)

1% more funds holding

Funds holding: 215218 (+3)

3% less capital invested

Capital invested by funds: $1.3B → $1.25B (-$41.1M)

Holders
218
Holders Change
+3
Holders Change %
+1.4%
% of All Funds
2.92%
Holding in Top 10
10
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+25%
% of All Funds
0.13%
New
31
Increased
88
Reduced
63
Closed
26
Calls
$18.1M
Puts
$7.88M
Net Calls
+$10.2M
Net Calls Change
-$2.9M
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
26
JP Morgan Chase
New York
$13.6M +$2.94M +208,490 +23%
SVCM
27
Saturn V Capital Management
Texas
$12.8M +$744K +52,752 +5%
ACM
28
Aisling Capital Management
New York
$12.6M
PHS
29
PFM Health Sciences
California
$11.4M +$10.1M +719,553 +348%
APM
30
Avidity Partners Management
Texas
$11.4M -$8.11M -575,000 -38%
OCA
31
Octagon Capital Advisors
New York
$11.1M
AG
32
Algert Global
California
$10.9M +$1.4M +98,968 +13%
Qube Research & Technologies (QRT)
33
Qube Research & Technologies (QRT)
United Kingdom
$10.3M +$1.56M +110,433 +15%
SCM
34
Soleus Capital Management
Connecticut
$10M -$23.6M -1,675,390 -67%
D.E. Shaw & Co
35
D.E. Shaw & Co
New York
$9.68M +$8.51M +603,470 +328%
Two Sigma Investments
36
Two Sigma Investments
New York
$9.58M +$1.55M +110,186 +16%
Northern Trust
37
Northern Trust
Illinois
$9.57M -$197K -13,992 -2%
Charles Schwab
38
Charles Schwab
California
$8.47M -$213K -15,130 -2%
Ensign Peak Advisors
39
Ensign Peak Advisors
Utah
$8.47M +$5.94M +421,115 +157%
Renaissance Technologies
40
Renaissance Technologies
New York
$8.37M +$6.52K +462 +0.1%
CC
41
Casdin Capital
New York
$7.8M +$2.26M +160,000 +34%
Adage Capital Partners
42
Adage Capital Partners
Massachusetts
$7.76M +$138K +9,800 +2%
PM
43
Prosight Management
Texas
$7.48M -$152K -10,748 -2%
PHP
44
Parkman Healthcare Partners
Connecticut
$7.31M +$959K +68,014 +13%
NCM
45
Nantahala Capital Management
Connecticut
$6.81M -$85K -6,029 -1%
GIM
46
Granahan Investment Management
Massachusetts
$6.76M -$5.01M -355,380 -39%
DCM
47
DAFNA Capital Management
California
$6.69M +$35.3K +2,500 +0.5%
Two Sigma Advisers
48
Two Sigma Advisers
New York
$6.18M -$463K -32,800 -6%
Dimensional Fund Advisors
49
Dimensional Fund Advisors
Texas
$5.72M +$1.9M +134,582 +41%
CS
50
Candriam SCA
Luxembourg
$5.53M -$1.36M -96,730 -18%

SNDX Hedge Fund Activity: Q1 2025 in Review

218 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q1 2025, worth a combined $1.25B — down 3.2% from $1.3B a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new SNDX positions and 26 closed out — a net gain of 5 holders — while 88 added to existing stakes and 63 trimmed.

The largest buyer was Eversept Partners, adding an estimated $54.6M. The largest seller was Wellington Management Group, cutting an estimated $59.2M.

  • 218 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q1 2025, up from 215 in Q4 2024.
  • Funds reported $1.25B of Syndax Pharmaceuticals stock for Q1 2025, down 3.2% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q1 2025 and 26 closed out, a net change of +5 holders.
  • The largest Syndax Pharmaceuticals buyer in Q1 2025 was Eversept Partners, an estimated $54.6M added.
  • The largest Syndax Pharmaceuticals seller in Q1 2025 was Wellington Management Group, an estimated $59.2M sold.

Based on aggregated 13F filings for Q1 2025.