Two Sigma Investments
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Two Sigma Investments’s Syndax Pharmaceuticals SNDX Stock Holding History

Two Sigma Investments’s Portfolio SNDX Stock Details SNDX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$36.9M Buy
1,579,596
+432,660
+38% +$9.4M 0.03% 630
2025
Q4 		$24.1M Buy
1,146,936
+434,277
+61% +$7.58M 0.03% 630
2025
Q3 		$11M Buy
712,659
+155,688
+28% +$2.04M 0.02% 912
2025
Q2 		$5.22M Sell
556,971
-223,038
-29% -$2.45M 0.01% 1202
2025
Q1 		$9.58M Buy
780,009
+110,186
+16% +$1.55M 0.02% 786
2024
Q4 		$8.86M Sell
669,823
-216,671
-24% -$3.71M 0.02% 810
2024
Q3 		$17.1M Sell
886,494
-44,453
-5% -$918K 0.04% 551
2024
Q2 		$19.1M Buy
930,947
+212,395
+30% +$4.44M 0.04% 477
2024
Q1 		$17.1M Buy
718,552
+182,614
+34% +$4.07M 0.04% 483
2023
Q4 		$11.6M Buy
535,938
+104,373
+24% +$1.6M 0.03% 614
2023
Q3 		$6.27M Buy
+431,565
New +$8.16M 0.02% 787
2023
Q2 		– Sell
-69,169
Closed -$1.46M – 3245
2023
Q1 		$1.46M Buy
+69,169
New +$1.72M ﹤0.01% 1629
2022
Q3 		– Sell
-94,474
Closed -$1.82M – 2795
2022
Q2 		$1.82M Sell
94,474
-129,584
-58% -$2.16M 0.01% 1250
2022
Q1 		$3.89M Sell
224,058
-98,662
-31% -$1.66M 0.01% 1034
2021
Q4 		$7.06M Buy
322,720
+212,740
+193% +$3.93M 0.02% 995
2021
Q3 		$2.1M Sell
109,980
-2,359
-2% -$39.3K ﹤0.01% 1943
2021
Q2 		$1.93M Sell
112,339
-129,075
-53% -$2.36M ﹤0.01% 1896
2021
Q1 		$5.4M Sell
241,414
-353,457
-59% -$7.99M 0.01% 993
2020
Q4 		$13.2M Buy
594,871
+368,182
+162% +$7.64M 0.04% 495
2020
Q3 		$3.35M Sell
226,689
-128,122
-36% -$1.95M 0.01% 1007
2020
Q2 		$5.26M Buy
354,811
+290,006
+448% +$4.42M 0.03% 626
2020
Q1 		$711K Buy
64,805
+8,611
+15% +$80.8K 0.01% 1685
2019
Q4 		$493K Buy
56,194
+38,459
+217% +$282K ﹤0.01% 2813
2019
Q3 		$132K Buy
+17,735
New +$162K ﹤0.01% 3273
2019
Q1 		– Sell
-13,487
Closed -$60K – 3434
2018
Q4 		$60K Sell
13,487
-9,578
-42% -$52.5K ﹤0.01% 2857
2018
Q3 		$186K Buy
+23,065
New +$164K ﹤0.01% 3026
2018
Q1 		– Sell
-30,930
Closed -$271K – 3484
2017
Q4 		$271K Buy
+30,930
New +$306K ﹤0.01% 2777

Other funds holding SNDX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
KCM
Kynam Capital Management Princeton, New Jersey $1.62B AUM 138.67% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
DM
Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return
EP
Eversept Partners New York $1.9B AUM 121.13% 1-Year Est. Return
KCM
Kingdon Capital Management New York $911M AUM 51.11% 1-Year Est. Return
HRCM
Hood River Capital Management Palm Beach Gardens, Florida $9.98B AUM 145.42% 1-Year Est. Return

Two Sigma Investments's SNDX Position: Q1 2026 in Review

Two Sigma Investments increased its Syndax Pharmaceuticals (SNDX) stake by 38% in Q1 2026, buying an estimated $9.4M and bringing the position to 1,579,596 shares worth $36.9M. The position accounts for 0.03% of the portfolio, ranked #630.

Two Sigma Investments first reported a position in SNDX in Q4 2017 and has held it in 27 quarters since. 246 funds tracked by Wall St. Rank hold SNDX as of Q1 2026.

  • Two Sigma Investments held 1,579,596 shares of Syndax Pharmaceuticals worth $36.9M as of Q1 2026.
  • Two Sigma Investments bought 432,660 Syndax Pharmaceuticals shares in Q1 2026, an estimated $9.4M.
  • Syndax Pharmaceuticals made up 0.03% of Two Sigma Investments's portfolio in Q1 2026, its #630 holding.
  • Two Sigma Investments first reported a position in Syndax Pharmaceuticals in Q4 2017 and has held it in 27 quarters since.
  • 246 funds tracked by Wall St. Rank held Syndax Pharmaceuticals as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.