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Summit Therapeutics

238 hedge funds and large institutions have $2.08B invested in Summit Therapeutics in 2025 Q2 according to their latest regulatory filings, with 73 funds opening new positions, 66 increasing their positions, 75 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more call options, than puts

Call options by funds: $126M | Put options by funds: $77.1M

62% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 45

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

12% more funds holding

Funds holding: 212238 (+26)

9% more capital invested

Capital invested by funds: $1.91B → $2.08B (+$173M)

0.21% less ownership

Funds ownership: 13.39%13.18% (-0.21%)

12% less repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 75

Holders
238
Holders Change
+26
Holders Change %
+12.26%
% of All Funds
3.13%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
73
Increased
66
Reduced
75
Closed
45
Calls
$126M
Puts
$77.1M
Net Calls
+$49.1M
Net Calls Change
+$69.3M
Name Holding Trade Value Shares
Change
Change in
Stake
Mariner
151
Mariner
Kansas
$250K +$268K +11,762 New
Raymond James Financial
152
Raymond James Financial
Florida
$249K +$267K +11,692 New
CW
153
CreativeOne Wealth
Kansas
$248K -$217K -9,499 -45%
OAM
154
Oxford Asset Management
United Kingdom
$245K +$263K +11,535 New
JF
155
Jump Financial
Illinois
$244K +$261K +11,452 New
NYLIM
156
New York Life Investment Management
New York
$241K -$5.08K -223 -2%
AAM
157
Advisors Asset Management
Colorado
$238K +$137 +6 +0.1%
SSG
158
Summit Securities Group
New York
$226K +$242K +10,602 New
Mirae Asset Global ETFs Holdings
159
Mirae Asset Global ETFs Holdings
Hong Kong
$213K -$1.26M -55,100 -84%
WIC
160
Willis Investment Counsel
Georgia
$213K
AWM
161
Arista Wealth Management
Nevada
$213K +$228K +10,000 New
AB
162
Amalgamated Bank
New York
$169K +$109K +4,758 +149%
California State Teachers Retirement System (CalSTRS)
163
California State Teachers Retirement System (CalSTRS)
California
$157K +$64.5K +2,828 +62%
MIM
164
MetLife Investment Management
New Jersey
$155K -$1.08M -47,428 -87%
Macquarie Group
165
Macquarie Group
Australia
$143K -$2.35M -103,008 -94%
QT
166
Quantbot Technologies
New York
$132K +$142K +6,207 New
Osaic Holdings
167
Osaic Holdings
Arizona
$129K -$136K -5,979 -50%
A
168
AlphaQuest
New York
$125K +$76.4K +3,349 +132%
OCM
169
Osterweis Capital Management
California
$106K
VIA
170
Virtus Investment Advisers
Connecticut
$99.3K -$103K -4,528 -49%
AF
171
Avanza Fonder
Sweden
$95.5K -$23.9K -1,048 -19%
IA
172
IFP Advisors
Florida
$92.9K +$97.2K +4,264 +4,264%
Fifth Third Bancorp
173
Fifth Third Bancorp
Ohio
$63.8K
PNC Financial Services Group
174
PNC Financial Services Group
Pennsylvania
$56.1K +$46K +2,018 +325%
Daiwa Securities Group
175
Daiwa Securities Group
Japan
$55K -$267K -11,695 -82%

SMMT Hedge Fund Activity: Q2 2025 in Review

238 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q2 2025, worth a combined $2.08B — up 9.1% from $1.91B a quarter earlier.

Buyers outnumbered sellers: 73 funds opened new SMMT positions and 45 closed out — a net gain of 28 holders — while 66 added to existing stakes and 75 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $212M. The largest seller was Vanguard Group, cutting an estimated $67.7M.

  • 238 institutional investors held Summit Therapeutics (SMMT) as of Q2 2025, up from 212 in Q1 2025.
  • Funds reported $2.08B of Summit Therapeutics stock for Q2 2025, up 9.1% quarter-over-quarter.
  • 73 funds opened new Summit Therapeutics positions in Q2 2025 and 45 closed out, a net change of +28 holders.
  • The largest Summit Therapeutics buyer in Q2 2025 was Baker Bros. Advisors, an estimated $212M added.
  • The largest Summit Therapeutics seller in Q2 2025 was Vanguard Group, an estimated $67.7M sold.

Based on aggregated 13F filings for Q2 2025.