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Summit Therapeutics

238 hedge funds and large institutions have $2.08B invested in Summit Therapeutics in 2025 Q2 according to their latest regulatory filings, with 73 funds opening new positions, 66 increasing their positions, 75 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more call options, than puts

Call options by funds: $126M | Put options by funds: $77.1M

62% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 45

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

12% more funds holding

Funds holding: 212238 (+26)

9% more capital invested

Capital invested by funds: $1.91B → $2.08B (+$173M)

0.21% less ownership

Funds ownership: 13.39%13.18% (-0.21%)

12% less repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 75

Holders
238
Holders Change
+26
Holders Change %
+12.26%
% of All Funds
3.13%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
73
Increased
66
Reduced
75
Closed
45
Calls
$126M
Puts
$77.1M
Net Calls
+$49.1M
Net Calls Change
+$69.3M
Name Holding Trade Value Shares
Change
Change in
Stake
N
51
Nuveen
North Carolina
$3.84M -$1.26M -55,444 -24%
SA
52
Sovran Advisors
California
$3.45M +$80.2K +3,519 +2%
CUAMC
53
China Universal Asset Management Company
China
$3.17M +$27.3K +1,196 +0.8%
Schroder Investment Management Group
54
Schroder Investment Management Group
United Kingdom
$3.08M -$2.03M -89,090 -38%
PAMI
55
Perseverance Asset Management International
Cayman Islands
$2.98M +$1.11M +48,569 +53%
Franklin Resources
56
Franklin Resources
California
$2.96M +$952K +41,756 +43%
D.E. Shaw & Co
57
D.E. Shaw & Co
New York
$2.92M +$2.46M +107,666 +362%
BAMF
58
BI Asset Management Fondsmaeglerselskab
Denmark
$2.66M +$2.85M +125,100 New
RhumbLine Advisers
59
RhumbLine Advisers
Massachusetts
$2.6M -$214K -9,366 -7%
GAM
60
Griffin Asset Management
New York
$2.54M +$49.5K +2,172 +2%
Cerity Partners
61
Cerity Partners
New York
$2.44M +$27.1K +1,190 +1%
Citigroup
62
Citigroup
New York
$2.41M -$4.15M -182,077 -62%
NIM
63
NEOS Investment Management
Connecticut
$2.28M +$201K +8,832 +9%
TE
64
Tema ETFs
New York
$2.28M +$201K +8,832 +9%
BHCM
65
Brevan Howard Capital Management
Jersey
$2.23M +$2.39M +104,660 New
Citadel Advisors
66
Citadel Advisors
Florida
$2.18M -$20.4M -896,323 -90%
Bank of Montreal
67
Bank of Montreal
Ontario, Canada
$2.14M -$1.9M -83,505 -45%
State Board of Administration of Florida Retirement System
68
State Board of Administration of Florida Retirement System
Florida
$2.07M +$1.47M +64,432 +195%
Envestnet Asset Management
69
Envestnet Asset Management
Illinois
$2.01M +$2.16M +94,550 New
HP
70
HealthInvest Partners
Sweden
$1.97M -$281K -12,340 -12%
JG
71
Jain Global
New York
$1.87M +$2.01M +87,943 New
EGM
72
Engineers Gate Manager
New York
$1.87M +$2M +87,830 New
UBS AM
73
UBS AM
Illinois
$1.85M +$1.98M +86,889 New
Royal Bank of Canada
74
Royal Bank of Canada
Ontario, Canada
$1.84M +$1.93M +84,613 +4,498%
Focus Partners Wealth
75
Focus Partners Wealth
Massachusetts
$1.84M +$44.8K +1,965 +2%

SMMT Hedge Fund Activity: Q2 2025 in Review

238 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q2 2025, worth a combined $2.08B — up 9.1% from $1.91B a quarter earlier.

Buyers outnumbered sellers: 73 funds opened new SMMT positions and 45 closed out — a net gain of 28 holders — while 66 added to existing stakes and 75 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $212M. The largest seller was Vanguard Group, cutting an estimated $67.7M.

  • 238 institutional investors held Summit Therapeutics (SMMT) as of Q2 2025, up from 212 in Q1 2025.
  • Funds reported $2.08B of Summit Therapeutics stock for Q2 2025, up 9.1% quarter-over-quarter.
  • 73 funds opened new Summit Therapeutics positions in Q2 2025 and 45 closed out, a net change of +28 holders.
  • The largest Summit Therapeutics buyer in Q2 2025 was Baker Bros. Advisors, an estimated $212M added.
  • The largest Summit Therapeutics seller in Q2 2025 was Vanguard Group, an estimated $67.7M sold.

Based on aggregated 13F filings for Q2 2025.