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Summit Therapeutics

206 hedge funds and large institutions have $2.06B invested in Summit Therapeutics in 2025 Q4 according to their latest regulatory filings, with 35 funds opening new positions, 75 increasing their positions, 65 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

15% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 65

1.42% more ownership

Funds ownership: 13.85%15.27% (+1.4%)

3% less capital invested

Capital invested by funds: $2.12B → $2.06B (-$64.2M)

11% less funds holding

Funds holding: 232206 (-26)

28% less call options, than puts

Call options by funds: $52.1M | Put options by funds: $72.2M

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

42% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 60

Holders
206
Holders Change
-26
Holders Change %
-11.21%
% of All Funds
2.51%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
35
Increased
75
Reduced
65
Closed
60
Calls
$52.1M
Puts
$72.2M
Net Calls
-$20.2M
Net Calls Change
-$43.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
26
Millennium Management
New York
$8.2M +$6.56M +348,503 +289%
Invesco
27
Invesco
Georgia
$8.07M +$663K +35,226 +8%
Manulife (Manufacturers Life Insurance)
28
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$7.71M +$2.66M +141,407 +47%
Tudor Investment Corp
29
Tudor Investment Corp
Connecticut
$7.4M +$1.43M +75,843 +22%
D.E. Shaw & Co
30
D.E. Shaw & Co
New York
$7.26M +$5.36M +284,657 +218%
Dimensional Fund Advisors
31
Dimensional Fund Advisors
Texas
$6.59M +$37.3K +1,980 +0.5%
QF
32
QVT Financial
New York
$6.31M
SC
33
Sculptor Capital
New York
$6.24M +$440K +23,400 +7%
AQR Capital Management
34
AQR Capital Management
Connecticut
$6.19M +$3.21M +170,386 +91%
Bank of New York Mellon
35
Bank of New York Mellon
New York
$6.19M -$252K -13,370 -4%
Barclays
36
Barclays
United Kingdom
$5.92M -$2.58M -137,387 -29%
Skandinaviska Enskilda Banken (SEB)
37
Skandinaviska Enskilda Banken (SEB)
Sweden
$5.91M
RAM
38
Readystate Asset Management
Illinois
$5.36M +$5.76M +306,184 New
Rafferty Asset Management
39
Rafferty Asset Management
New York
$5.03M -$966K -51,366 -15%
Schroder Investment Management Group
40
Schroder Investment Management Group
United Kingdom
$4.4M +$165K +8,772 +4%
Deutsche Bank
41
Deutsche Bank
Germany
$4.16M -$604K -32,096 -12%
N
42
Nuveen
North Carolina
$4.07M
Verition Fund Management
43
Verition Fund Management
Connecticut
$4.01M +$1.19M +63,388 +38%
WP
44
Woodline Partners
California
$3.75M
GAM
45
Griffin Asset Management
New York
$3.42M +$1.04M +55,265 +39%
Wells Fargo
46
Wells Fargo
California
$2.29M -$1.17M -61,990 -32%
Citigroup
47
Citigroup
New York
$2.27M -$563K -29,947 -19%
RhumbLine Advisers
48
RhumbLine Advisers
Massachusetts
$2.12M -$29.7K -1,581 -1%
CUAMC
49
China Universal Asset Management Company
China
$2.12M -$167K -8,903 -7%
Capital Fund Management (CFM)
50
Capital Fund Management (CFM)
France
$1.98M +$738K +39,238 +53%