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Summit Therapeutics

212 hedge funds and large institutions have $1.91B invested in Summit Therapeutics in 2025 Q1 according to their latest regulatory filings, with 42 funds opening new positions, 79 increasing their positions, 69 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 13 (+2)

27% more first-time investments, than exits

New positions opened: 42 | Existing positions closed: 33

15% more capital invested

Capital invested by funds: $1.65B → $1.91B (+$255M)

14% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 69

4% more funds holding

Funds holding: 203212 (+9)

0.83% more ownership

Funds ownership: 12.56%13.39% (+0.83%)

31% less call options, than puts

Call options by funds: $45.5M | Put options by funds: $65.7M

Holders
212
Holders Change
+9
Holders Change %
+4.43%
% of All Funds
2.84%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
42
Increased
79
Reduced
69
Closed
33
Calls
$45.5M
Puts
$65.7M
Net Calls
-$20.2M
Net Calls Change
-$2.98M
Name Holding Trade Value Shares
Change
Change in
Stake
Manulife (Manufacturers Life Insurance)
26
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$8.99M -$214K -10,650 -2%
Deutsche Bank
27
Deutsche Bank
Germany
$8.25M -$1.03M -51,189 -11%
CCM
28
Cutter Capital Management
New York
$7.72M +$8.02M +400,000 New
PCMH
29
Polymer Capital Management (HK)
Hong Kong
$7.64M +$3.54M +176,355 +80%
Invesco
30
Invesco
Georgia
$7.52M -$187K -9,345 -2%
Bank of America
31
Bank of America
North Carolina
$7.12M -$1.25M -62,346 -14%
QF
32
QVT Financial
New York
$6.95M
Bank of New York Mellon
33
Bank of New York Mellon
New York
$6.57M +$146K +7,265 +2%
Twin Tree Management
34
Twin Tree Management
Texas
$6.54M -$3.14M -156,697 -32%
EFM
35
E Fund Management
China
$5.7M -$13.7K -682 -0.2%
Citigroup
36
Citigroup
New York
$5.7M +$830K +41,375 +16%
Dimensional Fund Advisors
37
Dimensional Fund Advisors
Texas
$5.52M +$1.62M +80,692 +39%
Barclays
38
Barclays
United Kingdom
$4.93M -$1.5M -74,534 -23%
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$4.89M +$3.54M +176,275 +228%
Principal Financial Group
40
Principal Financial Group
Iowa
$4.75M +$828K +41,279 +20%
Schroder Investment Management Group
41
Schroder Investment Management Group
United Kingdom
$4.75M +$4.69M +233,597 New
N
42
Nuveen
North Carolina
$4.55M +$29.4K +1,467 +0.6%
Rafferty Asset Management
43
Rafferty Asset Management
New York
$4.43M -$1.64M -81,950 -26%
VOYA Investment Management
44
VOYA Investment Management
Georgia
$4.29M -$683K -34,041 -13%
Jane Street
45
Jane Street
New York
$4.17M +$1.62M +80,839 +60%
Russell Investments Group
46
Russell Investments Group
United Kingdom
$4.07M +$2.84M +141,664 +204%
SA
47
Sovran Advisors
California
$3.61M +$589K +29,354 +25%
Bank of Montreal
48
Bank of Montreal
Ontario, Canada
$3.55M +$2M +99,800 +118%
Lord, Abbett & Co
49
Lord, Abbett & Co
New Jersey
$3M +$3.12M +155,514 New
Ensign Peak Advisors
50
Ensign Peak Advisors
Utah
$2.91M +$3.03M +151,000 New

SMMT Hedge Fund Activity: Q1 2025 in Review

212 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q1 2025, worth a combined $1.91B — up 15% from $1.65B a quarter earlier.

Buyers outnumbered sellers: 42 funds opened new SMMT positions and 33 closed out — a net gain of 9 holders — while 79 added to existing stakes and 69 trimmed.

The largest buyer was Balyasny Asset Management, adding an estimated $26.4M. The largest seller was Millennium Management, cutting an estimated $23.3M.

  • 212 institutional investors held Summit Therapeutics (SMMT) as of Q1 2025, up from 203 in Q4 2024.
  • Funds reported $1.91B of Summit Therapeutics stock for Q1 2025, up 15% quarter-over-quarter.
  • 42 funds opened new Summit Therapeutics positions in Q1 2025 and 33 closed out, a net change of +9 holders.
  • The largest Summit Therapeutics buyer in Q1 2025 was Balyasny Asset Management, an estimated $26.4M added.
  • The largest Summit Therapeutics seller in Q1 2025 was Millennium Management, an estimated $23.3M sold.

Based on aggregated 13F filings for Q1 2025.