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Summit Therapeutics

238 hedge funds and large institutions have $2.08B invested in Summit Therapeutics in 2025 Q2 according to their latest regulatory filings, with 73 funds opening new positions, 66 increasing their positions, 75 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more call options, than puts

Call options by funds: $126M | Put options by funds: $77.1M

62% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 45

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

12% more funds holding

Funds holding: 212238 (+26)

9% more capital invested

Capital invested by funds: $1.91B → $2.08B (+$173M)

0.21% less ownership

Funds ownership: 13.39%13.18% (-0.21%)

12% less repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 75

Holders
238
Holders Change
+26
Holders Change %
+12.26%
% of All Funds
3.13%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
73
Increased
66
Reduced
75
Closed
45
Calls
$126M
Puts
$77.1M
Net Calls
+$49.1M
Net Calls Change
+$69.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
226
Sierra Ocean
California
$809 +$867 +38 New
RA
227
Rise Advisors
New York
$596 -$616 -27 -49%
DPW
228
DiNuzzo Private Wealth
Pennsylvania
$532
AF
229
Advisornet Financial
Minnesota
$468
RWM
230
Rialto Wealth Management
New York
$426 +$456 +20 New
TWD
231
True Wealth Design
Ohio
$384 +$319 +14 +350%
FFO
232
Fortitude Family Office
Arizona
$319 +$342 +15 New
SIC
233
SJS Investment Consulting
Ohio
$149 -$137 -6 -46%
BHWM
234
Bay Harbor Wealth Management
Maryland
$106 +$23 +1 +25%
SAM
235
Smartleaf Asset Management
Massachusetts
$103 +$114 +5 New
PWM
236
Parkworth Wealth Management
California
$85
HIA
237
HFM Investment Advisors
New Jersey
$43 +$23 +1 +100%
TPWA
238
Twin Peaks Wealth Advisors
California
$26 +$23 +1 New
Balyasny Asset Management
239
Balyasny Asset Management
Illinois
-$38.8M -1,703,180 Closed
SL
240
Siren LLC
Connecticut
-$13.4M -695,000 Closed
Adage Capital Partners
241
Adage Capital Partners
Massachusetts
-$10.4M -538,000 Closed
CCM
242
Cutter Capital Management
New York
-$7.72M -400,000 Closed
Twin Tree Management
243
Twin Tree Management
Texas
-$7.73M -339,085 Closed
Principal Financial Group
244
Principal Financial Group
Iowa
-$4.75M -246,429 Closed
Lord, Abbett & Co
245
Lord, Abbett & Co
New Jersey
-$3M -155,514 Closed
Ensign Peak Advisors
246
Ensign Peak Advisors
Utah
-$2.91M -151,000 Closed
SCM
247
Superstring Capital Management
New York
-$2.55M -132,019 Closed
SFAM
248
Springhill Fund Asset Management
Hong Kong
-$2.4M -124,307 Closed
DFCM
249
Dark Forest Capital Management
Puerto Rico
-$1.8M -93,548 Closed
IAMH
250
IvyRock Asset Management (HK)
Hong Kong
-$1.77M -91,741 Closed

SMMT Hedge Fund Activity: Q2 2025 in Review

238 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q2 2025, worth a combined $2.08B — up 9.1% from $1.91B a quarter earlier.

Buyers outnumbered sellers: 73 funds opened new SMMT positions and 45 closed out — a net gain of 28 holders — while 66 added to existing stakes and 75 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $212M. The largest seller was Vanguard Group, cutting an estimated $67.7M.

  • 238 institutional investors held Summit Therapeutics (SMMT) as of Q2 2025, up from 212 in Q1 2025.
  • Funds reported $2.08B of Summit Therapeutics stock for Q2 2025, up 9.1% quarter-over-quarter.
  • 73 funds opened new Summit Therapeutics positions in Q2 2025 and 45 closed out, a net change of +28 holders.
  • The largest Summit Therapeutics buyer in Q2 2025 was Baker Bros. Advisors, an estimated $212M added.
  • The largest Summit Therapeutics seller in Q2 2025 was Vanguard Group, an estimated $67.7M sold.

Based on aggregated 13F filings for Q2 2025.