|
1
|
Osaic Holdings
Scottsdale,
Arizona
|
$697
|
+$654
|
+282
|
New
|
|
|
2
|
IFP Advisors
Tampa,
Florida
|
$7
|
+$7
|
+3
|
New
|
|
|
3
|
Tang Capital Management
San Diego,
California
|
–
|
-$24.3M
|
-9,818,115
|
Closed
|
|
|
4
|
AyurMaya Capital Management Company
Portsmouth,
New Hampshire
|
–
|
-$23.1M
|
-9,334,735
|
Closed
|
|
|
5
|
|
–
|
-$14.3M
|
-5,805,096
|
Closed
|
|
|
6
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
–
|
-$11.5M
|
-4,649,865
|
Closed
|
|
|
7
|
Madison Avenue Partners
New York
|
–
|
-$10.2M
|
-4,142,640
|
Closed
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$10.1M
|
-4,079,706
|
Closed
|
|
|
9
|
|
–
|
-$9.88M
|
-4,001,711
|
Closed
|
|
|
10
|
venBio Partners
San Francisco,
California
|
–
|
-$9.4M
|
-3,806,410
|
Closed
|
|
|
11
|
Velan Capital Investment Management
Alpharetta,
Georgia
|
–
|
-$8.32M
|
-3,366,945
|
Closed
|
|
|
12
|
Tybourne Capital Management
Hong Kong
|
–
|
-$7.18M
|
-2,906,629
|
Closed
|
|
|
13
|
General Atlantic
New York
|
–
|
-$6.66M
|
-2,695,327
|
Closed
|
|
|
14
|
Samsara BioCapital
Palo Alto,
California
|
–
|
-$6.23M
|
-2,523,022
|
Closed
|
|
|
15
|
Palo Alto Investors
Palo Alto,
California
|
–
|
-$4.43M
|
-1,792,895
|
Closed
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$4.38M
|
-1,773,818
|
Closed
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
–
|
-$3.99M
|
-1,615,000
|
Closed
|
|
|
18
|
State Street
Boston,
Massachusetts
|
–
|
-$3.51M
|
-1,420,068
|
Closed
|
|
|
19
|
Balyasny Asset Management
Chicago,
Illinois
|
–
|
-$3.22M
|
-1,305,015
|
Closed
|
|
|
20
|
Alyeska Investment Group
Chicago,
Illinois
|
–
|
-$1.52M
|
-615,878
|
Closed
|
|
|
21
|
Renaissance Technologies
New York
|
–
|
-$1.48M
|
-599,800
|
Closed
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
–
|
-$1.48M
|
-598,151
|
Closed
|
|
|
23
|
|
–
|
-$1.46M
|
-590,846
|
Closed
|
|
|
24
|
Cantor Fitzgerald
New York
|
–
|
-$1.45M
|
-588,664
|
Closed
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
–
|
-$1.35M
|
-544,575
|
Closed
|
|
