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Soleno Therapeutics
SLNO

Overview Fund Activity

231 hedge funds and large institutions have $4.75B invested in Soleno Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 106 increasing their positions, 57 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
231
Holders Change
+15
Holders Change %
+6.94%
% of All Funds
3.1%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
50
Increased
106
Reduced
57
Closed
34
Calls
$163M
Puts
$181M
Net Calls
-$18.8M
Net Calls Change
-$67.6M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$280M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$290M
3
BlackRock
BlackRock
New York
$238M
4
Vanguard Group
Vanguard Group
Pennsylvania
$208M
5
NNPTE
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$42.1M

Top Sellers

1
PA
Perceptive Advisors
New York
$36.1M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$300M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
$0
4
NCM
Nantahala Capital Management
Connecticut
$83.9M
5
CC
Commodore Capital
New York
$51.1M
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$445M +$14M +167,110 +3%
VC
2
Vivo Capital
California
$332M -$41.9M -500,000 -11%
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$300M -$68.4M -816,732 -19%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$290M +$88.9M +1,061,064 +44%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$280M +$92.5M +1,104,385 +49%
BlackRock
6
BlackRock
New York
$238M +$78M +931,421 +49%
Vanguard Group
7
Vanguard Group
Pennsylvania
$208M +$52.1M +621,506 +33%
ACA
8
Avoro Capital Advisors
New York
$172M -$39.8M -475,000 -19%
Citadel Advisors
9
Citadel Advisors
Florida
$126M -$5.94M -70,883 -4%
Westfield Capital Management
10
Westfield Capital Management
Massachusetts
$120M +$18.3M +218,511 +18%
State Street
11
State Street
Massachusetts
$118M +$19.8M +235,784 +20%
Holocene Advisors
12
Holocene Advisors
New York
$96.6M -$3.68M -43,942 -4%
NCM
13
Nantahala Capital Management
Connecticut
$83.9M -$63.3M -755,673 -43%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$75.6M +$24M +286,660 +47%
CG
15
Carlyle Group
District of Columbia
$72.1M – – –
PCH
16
Polar Capital Holdings
United Kingdom
$68.5M +$26.6M +317,500 +64%
EA
17
Emerald Advisers
Pennsylvania
$56.4M +$9.08M +108,427 +19%
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$54.6M -$15.6M -185,784 -22%
Invesco
19
Invesco
Georgia
$54.1M +$15M +178,781 +38%
Millennium Management
20
Millennium Management
New York
$53.1M -$3.82M -45,570 -7%
Wellington Management Group
21
Wellington Management Group
Massachusetts
$52M -$6.08M -72,606 -10%
Capital World Investors
22
Capital World Investors
California
$51.5M +$12.6M +150,000 +32%
CC
23
Commodore Capital
New York
$51.1M -$45.2M -540,000 -47%
NNPTE
24
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$42.1M +$42.1M +502,374 New
AGP
25
Artia Global Partners
Florida
$41.4M -$339K -4,049 -0.8%
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