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Soleno Therapeutics
SLNO

Overview Fund Activity

216 hedge funds and large institutions have $3.9B invested in Soleno Therapeutics in 2025 Q1 according to their latest regulatory filings, with 70 funds opening new positions, 73 increasing their positions, 55 reducing their positions, and 17 closing their positions.

Holders
216
Holders Change
+51
Holders Change %
+30.91%
% of All Funds
2.93%
Holding in Top 10
19
Holding in Top 10 Change
+11
Holding in Top 10 Change %
+137.5%
% of All Funds
0.26%
New
70
Increased
73
Reduced
55
Closed
17
Calls
$285M
Puts
$236M
Net Calls
+$48.8M
Net Calls Change
+$51.8M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$314M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$160M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$65.4M
4
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$172M
5
Citadel Advisors
5
Citadel Advisors
Florida
$113M

Top Sellers

1
NCM
1
Nantahala Capital Management
Connecticut
$126M
2
VC
2
Vivo Capital
California
$319M
3
VPC
3
Vestal Point Capital
New York
$0
4
CG
4
Carlyle Group
District of Columbia
$61.4M
5
CC
5
Commodore Capital
New York
$82.2M
Name Market Value Shares Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$370M 5,140,899 -47,366 -0.9%
VC
2
Vivo Capital
California
$319M 4,458,294 -1,833,557 -29%
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$314M 4,392,696 +1,616,720 +58%
ACA
4
Avoro Capital Advisors
New York
$180M 2,525,000 – –
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$172M 2,400,418 +769,700 +47%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$160M 2,233,473 +1,420,446 +175%
BlackRock
7
BlackRock
New York
$137M 1,913,326 -96,464 -5%
Vanguard Group
8
Vanguard Group
Pennsylvania
$133M 1,866,326 -18,207 -1%
NCM
9
Nantahala Capital Management
Connecticut
$126M 1,757,023 -2,171,943 -55%
Citadel Advisors
10
Citadel Advisors
Florida
$113M 1,576,044 +603,634 +62%
PA
11
Perceptive Advisors
New York
$108M 1,506,602 +5,562 +0.4%
Westfield Capital Management
12
Westfield Capital Management
Massachusetts
$86.5M 1,211,245 +329,785 +37%
Holocene Advisors
13
Holocene Advisors
New York
$85.5M 1,196,990 +241,523 +25%
State Street
14
State Street
Massachusetts
$83.5M 1,169,199 -177,820 -13%
CC
15
Commodore Capital
New York
$82.2M 1,150,000 -375,000 -25%
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$65.4M 915,995 +915,995 New
CG
17
Carlyle Group
District of Columbia
$61.4M 860,980 -514,666 -37%
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$59.9M 837,836 -14,002 -2%
SL
19
Siren LLC
Connecticut
$52M 727,337 +375,519 +107%
Wellington Management Group
20
Wellington Management Group
Massachusetts
$49.6M 693,644 -88,621 -11%
Millennium Management
21
Millennium Management
New York
$48.5M 679,291 +202,490 +42%
Goldman Sachs
22
Goldman Sachs
New York
$45.2M 633,110 +213,667 +51%
Geode Capital Management
23
Geode Capital Management
Massachusetts
$44M 615,736 +16,617 +3%
PHS
24
PFM Health Sciences
California
$42.5M 595,206 +287,703 +94%
EA
25
Emerald Advisers
Pennsylvania
$40.3M 564,481 -16,438 -3%
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