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Soleno Therapeutics
SLNO

Overview Fund Activity

216 hedge funds and large institutions have $3.9B invested in Soleno Therapeutics in 2025 Q1 according to their latest regulatory filings, with 70 funds opening new positions, 73 increasing their positions, 55 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
216
Holders Change
+51
Holders Change %
+30.91%
% of All Funds
2.93%
Holding in Top 10
19
Holding in Top 10 Change
+11
Holding in Top 10 Change %
+137.5%
% of All Funds
0.26%
New
70
Increased
73
Reduced
55
Closed
17
Calls
$285M
Puts
$236M
Net Calls
+$48.8M
Net Calls Change
+$51.8M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$314M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$160M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$65.4M
4
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$172M
5
Citadel Advisors
5
Citadel Advisors
Florida
$113M

Top Sellers

1
NCM
1
Nantahala Capital Management
Connecticut
$126M
2
VC
2
Vivo Capital
California
$319M
3
VPC
3
Vestal Point Capital
New York
$0
4
CG
4
Carlyle Group
District of Columbia
$61.4M
5
CC
5
Commodore Capital
New York
$82.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Manulife (Manufacturers Life Insurance)
76
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.79M +$135K +1,884 +4%
QC
77
Quadrature Capital
United Kingdom
$3.69M +$3.69M +51,762 New
FMI
78
F/M Investments
District of Columbia
$3.63M +$212K +2,973 +6%
Susquehanna International Group
79
Susquehanna International Group
Pennsylvania
$3.59M +$1.7M +23,742 +89%
Swiss National Bank
80
Swiss National Bank
Switzerland
$3.58M +$300K +4,200 +9%
AAA
81
Affinity Asset Advisors
New York
$3.57M -$5.72M -80,000 -62%
6CM
82
683 Capital Management
New York
$3.57M – – –
TCM
83
Tang Capital Management
California
$3.57M – – –
EI
84
EAM Investors
California
$3.54M +$3.54M +49,548 New
HCA
85
Harbor Capital Advisors
Illinois
$3.35M +$688K +9,635 +26%
Rafferty Asset Management
86
Rafferty Asset Management
New York
$3.31M -$1.44M -20,127 -30%
EAM
87
Exome Asset Management
New York
$3.1M -$2.42M -33,844 -44%
UBS AM
88
UBS AM
Illinois
$2.91M +$944K +13,211 +48%
YIH
89
Y-Intercept (HK)
Hong Kong
$2.89M +$2.89M +40,425 New
FAM
90
Fred Alger Management
New York
$2.89M +$1.83M +25,589 +173%
RCAP
91
Resolute Capital Asset Partners
Colorado
$2.86M +$2.86M +40,000 New
AllianceBernstein
92
AllianceBernstein
Tennessee
$2.7M +$995K +13,921 +58%
HP
93
HealthInvest Partners
Sweden
$2.65M +$440K +6,158 +20%
Universal-Beteiligungs- und Servicegesellschaft
94
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.61M +$2.61M +36,495 New
RhumbLine Advisers
95
RhumbLine Advisers
Massachusetts
$2.6M +$146K +2,044 +6%
SSA
96
Schonfeld Strategic Advisors
New York
$2.55M +$2.55M +35,706 New
GGHC
97
Gilder Gagnon Howe & Co
New York
$2.36M +$2.36M +33,086 New
GIM
98
Granahan Investment Management
Massachusetts
$2.32M +$2.32M +32,491 New
APM
99
Avidity Partners Management
Texas
$2.29M +$2.29M +32,000 New
California State Teachers Retirement System (CalSTRS)
100
California State Teachers Retirement System (CalSTRS)
California
$2.24M +$666K +9,317 +42%
2 3
4
5 6