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Soleno Therapeutics
SLNO

Overview Fund Activity

231 hedge funds and large institutions have $4.75B invested in Soleno Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 106 increasing their positions, 57 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
231
Holders Change
+15
Holders Change %
+6.94%
% of All Funds
3.1%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
50
Increased
106
Reduced
57
Closed
34
Calls
$163M
Puts
$181M
Net Calls
-$18.8M
Net Calls Change
-$67.6M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$280M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$290M
3
BlackRock
BlackRock
New York
$238M
4
Vanguard Group
Vanguard Group
Pennsylvania
$208M
5
NNPTE
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$42.1M

Top Sellers

1
PA
Perceptive Advisors
New York
$36.1M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$300M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
$0
4
NCM
Nantahala Capital Management
Connecticut
$83.9M
5
CC
Commodore Capital
New York
$51.1M
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of New York Mellon
26
Bank of New York Mellon
New York
$40.7M +$15.3M +183,201 +61%
SL
27
Siren LLC
Connecticut
$39.2M -$21.8M -259,995 -36%
Alyeska Investment Group
28
Alyeska Investment Group
Illinois
$37.3M -$7.03M -83,857 -16%
Morgan Stanley
29
Morgan Stanley
New York
$36.9M +$19.1M +227,695 +107%
PA
30
Perceptive Advisors
New York
$36.1M -$90.2M -1,076,163 -71%
RI
31
RTW Investments
New York
$35.6M +$35.6M +424,408 New
SI
32
Sofinnova Investments
California
$34.8M -$5.8M -69,252 -14%
Susquehanna International Group
33
Susquehanna International Group
Pennsylvania
$34.6M +$30.4M +362,433 +721%
CCM
34
Catalio Capital Management
New York
$34.3M +$20.9M +248,982 +155%
PHS
35
PFM Health Sciences
California
$34.1M -$15.8M -188,004 -32%
EMFAT
36
Emerald Mutual Fund Advisers Trust
Pennsylvania
$34M +$2.84M +33,954 +9%
RAM
37
Readystate Asset Management
Illinois
$32.9M +$24.6M +293,387 +295%
DCM
38
Driehaus Capital Management
Illinois
$32.2M +$11.4M +136,536 +55%
Balyasny Asset Management
39
Balyasny Asset Management
Illinois
$30.3M +$28.8M +344,273 +1,986%
WP
40
Woodline Partners
California
$29.3M – – –
Goldman Sachs
41
Goldman Sachs
New York
$28.9M -$24.1M -288,138 -46%
Northern Trust
42
Northern Trust
Illinois
$27.5M +$8.07M +96,304 +41%
Charles Schwab
43
Charles Schwab
California
$24.8M +$6.89M +82,278 +38%
TLP
44
Tri Locum Partners
New York
$24.2M +$4.52M +53,960 +23%
Marshall Wace
45
Marshall Wace
United Kingdom
$24.2M +$13.8M +164,580 +133%
DP
46
Diadema Partners
New Jersey
$23.8M +$16M +191,150 +206%
CM
47
Caption Management
Oklahoma
$22.1M -$2.66M -31,713 -11%
JPMorgan Chase & Co
48
JPMorgan Chase & Co
New York
$21.7M +$19.4M +231,579 +846%
Assenagon Asset Management
49
Assenagon Asset Management
Luxembourg
$21M -$15.4M -184,073 -42%
TCM
50
TimesSquare Capital Management
New York
$20.7M +$3.42M +40,769 +20%
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