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Soleno Therapeutics
SLNO

Overview Fund Activity

216 hedge funds and large institutions have $3.9B invested in Soleno Therapeutics in 2025 Q1 according to their latest regulatory filings, with 70 funds opening new positions, 73 increasing their positions, 55 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
216
Holders Change
+51
Holders Change %
+30.91%
% of All Funds
2.93%
Holding in Top 10
19
Holding in Top 10 Change
+11
Holding in Top 10 Change %
+137.5%
% of All Funds
0.26%
New
70
Increased
73
Reduced
55
Closed
17
Calls
$285M
Puts
$236M
Net Calls
+$48.8M
Net Calls Change
+$51.8M

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
$314M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$160M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
$65.4M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$172M
5
Citadel Advisors
Citadel Advisors
Florida
$113M

Top Sellers

1
NCM
Nantahala Capital Management
Connecticut
$126M
2
VC
Vivo Capital
California
$319M
3
VPC
Vestal Point Capital
New York
$0
4
CG
Carlyle Group
District of Columbia
$61.4M
5
CC
Commodore Capital
New York
$82.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Alyeska Investment Group
26
Alyeska Investment Group
Illinois
$37.8M +$7.51M +105,128 +25%
PCH
27
Polar Capital Holdings
United Kingdom
$35.7M +$35.7M +500,000 New
FLSM
28
Frazier Life Sciences Management
California
$35.7M -$14.3M -200,000 -29%
AGP
29
Artia Global Partners
Florida
$35.6M +$289K +4,049 +0.8%
SI
30
Sofinnova Investments
California
$34.6M -$19.5M -272,777 -36%
Invesco
31
Invesco
Georgia
$33.4M +$32.5M +455,181 +3,789%
Capital World Investors
32
Capital World Investors
California
$33.2M +$33.2M +464,833 New
Assenagon Asset Management
33
Assenagon Asset Management
Luxembourg
$31M +$31M +434,514 New
Bank of America
34
Bank of America
North Carolina
$30.7M +$27.2M +380,110 +761%
EMFAT
35
Emerald Mutual Fund Advisers Trust
Pennsylvania
$26.6M +$223K +3,123 +0.8%
WP
36
Woodline Partners
California
$25M +$3.44M +48,102 +16%
Bank of New York Mellon
37
Bank of New York Mellon
New York
$21.6M +$16.8M +234,649 +345%
CM
38
Caption Management
Oklahoma
$21.1M +$19.4M +271,852 +1,174%
TCM
39
TCG Crossover Management
California
$19.6M -$19.6M -275,000 -50%
SFM
40
Soros Fund Management
New York
$19.3M +$19.3M +270,663 New
LGM
41
Logos Global Management
California
$17.9M -$7.15M -100,000 -29%
DCM
42
Driehaus Capital Management
Illinois
$17.7M +$17.7M +247,737 New
TLP
43
Tri Locum Partners
New York
$16.8M +$16.8M +234,920 New
Northern Trust
44
Northern Trust
Illinois
$16.6M +$389K +5,447 +2%
Qube Research & Technologies (QRT)
45
Qube Research & Technologies (QRT)
United Kingdom
$16M +$7.48M +104,673 +88%
Charles Schwab
46
Charles Schwab
California
$15.3M -$255K -3,566 -2%
Morgan Stanley
47
Morgan Stanley
New York
$15.2M +$152K +2,122 +1%
TCM
48
TimesSquare Capital Management
New York
$14.8M -$9.52M -133,174 -39%
SC
49
Samlyn Capital
New York
$13.6M -$13.4M -187,221 -50%
Comerica Bank
50
Comerica Bank
Texas
$13.4M +$4.78M +66,880 +55%
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