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Soleno Therapeutics
SLNO

Overview Fund Activity

228 hedge funds and large institutions have $4.72B invested in Soleno Therapeutics in 2025 Q2 according to their latest regulatory filings, with 48 funds opening new positions, 105 increasing their positions, 57 reducing their positions, and 34 closing their positions.

Holders
228
Holders Change
+12
Holders Change %
+5.56%
% of All Funds
3.06%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
48
Increased
105
Reduced
57
Closed
34
Calls
$130M
Puts
$118M
Net Calls
+$11.8M
Net Calls Change
-$37M

Top Buyers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$280M
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$290M
3
BlackRock
3
BlackRock
New York
$238M
4
Vanguard Group
4
Vanguard Group
Pennsylvania
$208M
5
NNPTE
5
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$42.1M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$36.1M
2
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$300M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
NCM
4
Nantahala Capital Management
Connecticut
$83.9M
5
CC
5
Commodore Capital
New York
$51.1M
Name Market Value Shares Shares
Change 		Shares
Change %
Bank of New York Mellon
26
Bank of New York Mellon
New York
$40.7M 485,865 +183,201 +61%
SL
27
Siren LLC
Connecticut
$39.2M 467,342 -259,995 -36%
Alyeska Investment Group
28
Alyeska Investment Group
Illinois
$37.3M 445,352 -83,857 -16%
Morgan Stanley
29
Morgan Stanley
New York
$36.9M 440,054 +227,695 +107%
PA
30
Perceptive Advisors
New York
$36.1M 430,439 -1,076,163 -71%
RI
31
RTW Investments
New York
$35.6M 424,408 +424,408 New
SI
32
Sofinnova Investments
California
$34.8M 415,219 -69,252 -14%
CCM
33
Catalio Capital Management
New York
$34.3M 409,944 +248,982 +155%
PHS
34
PFM Health Sciences
California
$34.1M 407,202 -188,004 -32%
EMFAT
35
Emerald Mutual Fund Advisers Trust
Pennsylvania
$34M 405,651 +33,954 +9%
RAM
36
Readystate Asset Management
Illinois
$32.9M 392,809 +293,387 +295%
DCM
37
Driehaus Capital Management
Illinois
$32.2M 384,273 +136,536 +55%
Balyasny Asset Management
38
Balyasny Asset Management
Illinois
$30.3M 361,605 +344,273 +1,986%
WP
39
Woodline Partners
California
$29.3M 349,664 – –
Goldman Sachs
40
Goldman Sachs
New York
$28.9M 344,972 -288,138 -46%
Northern Trust
41
Northern Trust
Illinois
$27.5M 328,640 +96,304 +41%
Charles Schwab
42
Charles Schwab
California
$24.8M 296,262 +82,278 +38%
TLP
43
Tri Locum Partners
New York
$24.2M 288,880 +53,960 +23%
Marshall Wace
44
Marshall Wace
United Kingdom
$24.2M 288,334 +164,580 +133%
DP
45
Diadema Partners
New Jersey
$23.8M 284,152 +191,150 +206%
CM
46
Caption Management
Oklahoma
$22.1M 263,287 -31,713 -11%
JPMorgan Chase & Co
47
JPMorgan Chase & Co
New York
$21.7M 258,965 +231,579 +846%
Assenagon Asset Management
48
Assenagon Asset Management
Luxembourg
$21M 250,441 -184,073 -42%
TCM
49
TimesSquare Capital Management
New York
$20.7M 247,369 +40,769 +20%
Comerica Bank
50
Comerica Bank
Texas
$20.6M 245,349 +57,256 +30%
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