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Solid Biosciences

127 hedge funds and large institutions have $502M invested in Solid Biosciences in 2025 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 38 increasing their positions, 36 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,465% more call options, than puts

Call options by funds: $4.33M | Put options by funds: $277K

108% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 12

25% more capital invested

Capital invested by funds: $400M → $502M (+$102M)

11% more funds holding

Funds holding: 114127 (+13)

6% more repeat investments, than reductions

Existing positions increased: 38 | Existing positions reduced: 36

1.56% less ownership

Funds ownership: 106.06%104.5% (-1.6%)

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

Holders
127
Holders Change
+13
Holders Change %
+11.4%
% of All Funds
1.67%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
25
Increased
38
Reduced
36
Closed
12
Calls
$4.33M
Puts
$277K
Net Calls
+$4.06M
Net Calls Change
+$3.02M
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$73M -$427K -73,107 -0.6%
BCLSI
2
Bain Capital Life Sciences Investors
Massachusetts
$48.8M
SL
3
Siren LLC
Connecticut
$45.8M
RCM
4
RA Capital Management
Massachusetts
$35.9M +$585 +100 +0%
BlackRock
5
BlackRock
New York
$29.2M -$1.14M -194,965 -4%
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$24.7M -$16M -2,729,484 -41%
Vanguard Group
7
Vanguard Group
Pennsylvania
$19M -$1.65M -281,697 -8%
VPC
8
Vestal Point Capital
New York
$18.4M +$8.6M +1,470,000 +98%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$18M -$1.55M -264,273 -8%
Citadel Advisors
10
Citadel Advisors
Florida
$16M +$406K +69,404 +3%
RG
11
Redmile Group
California
$11.7M -$97K -16,584 -0.9%
NCM
12
Nantahala Capital Management
Connecticut
$10.5M -$23.8K -4,078 -0.2%
Alyeska Investment Group
13
Alyeska Investment Group
Illinois
$10.4M +$245K +41,984 +3%
MB
14
MPM BioImpact
Massachusetts
$10.1M
Franklin Resources
15
Franklin Resources
California
$9.87M +$345 +59 +0%
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$8.22M +$391K +66,948 +5%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$7.94M -$1.3M -222,910 -15%
State Street
18
State Street
Massachusetts
$6.75M +$829K +141,847 +15%
FC
19
Finepoint Capital
Massachusetts
$5.93M
AC
20
Armistice Capital
New York
$5.78M +$3.13M +536,000 +134%
Millennium Management
21
Millennium Management
New York
$5.61M -$1.11M -189,672 -17%
Bank of America
22
Bank of America
North Carolina
$4.87M -$202K -34,604 -4%
Balyasny Asset Management
23
Balyasny Asset Management
Illinois
$4.52M +$1.44M +245,485 +50%
UBS Group
24
UBS Group
Switzerland
$4.47M -$282K -48,150 -6%
Goldman Sachs
25
Goldman Sachs
New York
$4.17M +$1.72M +294,872 +77%

SLDB Hedge Fund Activity: Q3 2025 in Review

127 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Solid Biosciences (SLDB) for Q3 2025, worth a combined $502M — up 25% from $400M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new SLDB positions and 12 closed out — a net gain of 13 holders — while 38 added to existing stakes and 36 trimmed.

The largest buyer was Vestal Point Capital, adding an estimated $8.6M. The largest seller was Adage Capital Partners, cutting an estimated $16M.

  • 127 institutional investors held Solid Biosciences (SLDB) as of Q3 2025, up from 114 in Q2 2025.
  • Funds reported $502M of Solid Biosciences stock for Q3 2025, up 25% quarter-over-quarter.
  • 25 funds opened new Solid Biosciences positions in Q3 2025 and 12 closed out, a net change of +13 holders.
  • The largest Solid Biosciences buyer in Q3 2025 was Vestal Point Capital, an estimated $8.6M added.
  • The largest Solid Biosciences seller in Q3 2025 was Adage Capital Partners, an estimated $16M sold.

Based on aggregated 13F filings for Q3 2025.