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Solid Biosciences
SLDB

124 hedge funds and large institutions have $292M invested in Solid Biosciences in 2025 Q1 according to their latest regulatory filings, with 49 funds opening new positions, 43 increasing their positions, 16 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

227% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 15

169% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 16

101% more capital invested

Capital invested by funds: $145M → $292M (+$146M)

38% more funds holding

Funds holding: 90 → 124 (+34)

10.83% more ownership

Funds ownership: 90.92% → 101.75% (+11%)

0% more call options, than puts

Call options by funds: $714K | Put options by funds: $714K

Holders
124
Holders Change
+34
Holders Change %
+37.78%
% of All Funds
1.66%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
49
Increased
43
Reduced
16
Closed
15
Calls
$714K
Puts
$714K
Net Calls
–
Net Calls Change
-$2.28M

Top Buyers

Rank Fund Capital Flow
1
CC
Commodore Capital
New York
+$24.9M
2
PA
Perceptive Advisors
New York
+$21.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$21.3M
4
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$16.6M
5
SL
Siren LLC
Connecticut
+$15.7M

Top Sellers

Rank Fund Capital Flow
1
VPC
Vestal Point Capital
New York
-$4.69M
2
JP Morgan Chase
JP Morgan Chase
New York
-$4.02M
3
LCM
Laurion Capital Management
New York
-$1.02M
4
Millennium Management
Millennium Management
New York
-$793K
5
N
Nuveen
North Carolina
-$661K
Name Holding Trade Value Shares
Change 		Change in
Stake
PA
1
Perceptive Advisors
New York
$44.1M +$21.4M +5,000,000 +72%
BCLSI
2
Bain Capital Life Sciences Investors
Massachusetts
$29.3M +$16.6M +3,877,087 +96%
SL
3
Siren LLC
Connecticut
$27.4M +$15.7M +3,666,864 +98%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$24.9M +$21.3M +4,981,400 +285%
CC
5
Commodore Capital
New York
$21.6M +$24.9M +5,825,000 New
RCM
6
RA Capital Management
Massachusetts
$16M – – –
Fidelity Investments
7
Fidelity Investments
Massachusetts
$13M +$14.9M +3,471,183 +7,432%
VA
8
VR Adviser
New York
$9.18M +$10.6M +2,481,400 New
Vanguard Group
9
Vanguard Group
Pennsylvania
$9.1M +$4.53M +1,059,192 +76%
BlackRock
10
BlackRock
New York
$7.96M +$1.24M +290,269 +16%
RG
11
Redmile Group
California
$7.47M +$6.01M +1,403,925 +228%
Citadel Advisors
12
Citadel Advisors
Florida
$6.98M +$4.01M +937,465 +99%
VPC
13
Vestal Point Capital
New York
$6.49M -$4.69M -1,096,442 -38%
MIM
14
Monashee Investment Management
Massachusetts
$6.19M +$5.11M +1,193,412 +249%
MB
15
MPM BioImpact
Massachusetts
$6.08M +$7.03M +1,642,356 New
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$6.07M +$5.54M +1,294,450 +374%
BCM
17
Boxer Capital Management
California
$4.59M +$5.31M +1,240,700 New
Franklin Resources
18
Franklin Resources
California
$4.59M +$5.31M +1,240,700 New
FC
19
Finepoint Capital
Massachusetts
$3.56M – – –
CC
20
Casdin Capital
New York
$2.87M +$3.32M +775,000 New
EC
21
EcoR1 Capital
California
$2.75M +$3.19M +744,450 New
WP
22
Woodline Partners
California
$2.34M +$2.71M +631,823 New
Balyasny Asset Management
23
Balyasny Asset Management
Illinois
$2.32M +$2.69M +627,274 New
Millennium Management
24
Millennium Management
New York
$1.98M -$793K -185,212 -26%
Geode Capital Management
25
Geode Capital Management
Massachusetts
$1.96M +$90.2K +21,057 +4%
1
2 3 4 5

SLDB Hedge Fund Activity: Q1 2025 in Review

124 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Solid Biosciences (SLDB) for Q1 2025, worth a combined $292M — up 101% from $145M a quarter earlier.

Buyers outnumbered sellers: 49 funds opened new SLDB positions and 15 closed out — a net gain of 34 holders — while 43 added to existing stakes and 16 trimmed.

The largest buyer was Commodore Capital, opening a new position worth an estimated $24.9M. The largest seller was Vestal Point Capital, cutting an estimated $4.69M.

  • 124 institutional investors held Solid Biosciences (SLDB) as of Q1 2025, up from 90 in Q4 2024.
  • Funds reported $292M of Solid Biosciences stock for Q1 2025, up 101% quarter-over-quarter.
  • 49 funds opened new Solid Biosciences positions in Q1 2025 and 15 closed out, a net change of +34 holders.
  • The largest Solid Biosciences buyer in Q1 2025 was Commodore Capital, an estimated $24.9M added.
  • The largest Solid Biosciences seller in Q1 2025 was Vestal Point Capital, an estimated $4.69M sold.

Based on aggregated 13F filings for Q1 2025.