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Solid Biosciences
SLDB

124 hedge funds and large institutions have $292M invested in Solid Biosciences in 2025 Q1 according to their latest regulatory filings, with 49 funds opening new positions, 43 increasing their positions, 16 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

227% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 15

169% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 16

101% more capital invested

Capital invested by funds: $145M → $292M (+$146M)

38% more funds holding

Funds holding: 90 → 124 (+34)

10.83% more ownership

Funds ownership: 90.92% → 101.75% (+11%)

0% more call options, than puts

Call options by funds: $714K | Put options by funds: $714K

Holders
124
Holders Change
+34
Holders Change %
+37.78%
% of All Funds
1.66%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
49
Increased
43
Reduced
16
Closed
15
Calls
$714K
Puts
$714K
Net Calls
–
Net Calls Change
-$2.28M

Top Buyers

Rank Fund Capital Flow
1
CC
Commodore Capital
New York
+$24.9M
2
PA
Perceptive Advisors
New York
+$21.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$21.3M
4
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$16.6M
5
SL
Siren LLC
Connecticut
+$15.7M

Top Sellers

Rank Fund Capital Flow
1
VPC
Vestal Point Capital
New York
-$4.69M
2
JP Morgan Chase
JP Morgan Chase
New York
-$4.02M
3
LCM
Laurion Capital Management
New York
-$1.02M
4
Millennium Management
Millennium Management
New York
-$793K
5
N
Nuveen
North Carolina
-$661K
Name Holding Trade Value Shares
Change 		Change in
Stake
Wellington Management Group
126
Wellington Management Group
Massachusetts
– -$498K -124,551 Closed
Prudential Financial
127
Prudential Financial
New Jersey
– -$436K -109,105 Closed
CSS
128
Cubist Systematic Strategies
Connecticut
– -$262K -65,613 Closed
D.E. Shaw & Co
129
D.E. Shaw & Co
New York
– -$208K -51,972 Closed
Los Angeles Capital Management
130
Los Angeles Capital Management
California
– -$172K -42,989 Closed
Qube Research & Technologies (QRT)
131
Qube Research & Technologies (QRT)
United Kingdom
– -$149K -37,277 Closed
Two Sigma Advisers
132
Two Sigma Advisers
New York
– -$97.5K -24,373 Closed
AG
133
Algert Global
California
– -$88K -22,089 Closed
EGM
134
Engineers Gate Manager
New York
– -$86.5K -21,622 Closed
SPA
135
Sherbrooke Park Advisers
New York
– -$63.1K -15,768 Closed
Manulife (Manufacturers Life Insurance)
136
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$40.6K -10,155 Closed
CC
137
Corton Capital
Ontario, Canada
– -$40.6K -10,152 Closed
Belvedere Trading
138
Belvedere Trading
Illinois
– -$3.6K -901 Closed
2 3 4 5
6

SLDB Hedge Fund Activity: Q1 2025 in Review

124 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Solid Biosciences (SLDB) for Q1 2025, worth a combined $292M — up 101% from $145M a quarter earlier.

Buyers outnumbered sellers: 49 funds opened new SLDB positions and 15 closed out — a net gain of 34 holders — while 43 added to existing stakes and 16 trimmed.

The largest buyer was Commodore Capital, opening a new position worth an estimated $24.9M. The largest seller was Vestal Point Capital, cutting an estimated $4.69M.

  • 124 institutional investors held Solid Biosciences (SLDB) as of Q1 2025, up from 90 in Q4 2024.
  • Funds reported $292M of Solid Biosciences stock for Q1 2025, up 101% quarter-over-quarter.
  • 49 funds opened new Solid Biosciences positions in Q1 2025 and 15 closed out, a net change of +34 holders.
  • The largest Solid Biosciences buyer in Q1 2025 was Commodore Capital, an estimated $24.9M added.
  • The largest Solid Biosciences seller in Q1 2025 was Vestal Point Capital, an estimated $4.69M sold.

Based on aggregated 13F filings for Q1 2025.