Solid Biosciences
SLDB
130 hedge funds and large institutions have $459M invested in Solid Biosciences in 2025 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 36 increasing their positions, 47 reducing their positions, and 11 closing their positions.
23,267% more call options, than puts
Call options by funds: $3.5M | Put options by funds: $15K
50% more funds holding in top 10
Funds holding in top 10: 2 → 3 (+1)
27% more first-time investments, than exits
New positions opened: 14 | Existing positions closed: 11
2% more funds holding
Funds holding: 127 → 130 (+3)
0.05% less ownership
Funds ownership: 104.5% → 104.45% (-0.05%)
9% less capital invested
Capital invested by funds: $502M → $459M (-$43.1M)
23% less repeat investments, than reductions
Existing positions increased: 36 | Existing positions reduced: 47
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VPC
Vestal Point Capital
New York
|
+$15.4M |
| 2 |
AC
Armistice Capital
New York
|
+$9.08M |
| 3 |
MIM
Monashee Investment Management
Boston,
Massachusetts
|
+$7.32M |
| 4 |
Point72 Asset Management
Stamford,
Connecticut
|
+$5.87M |
| 5 |
BC
Birchview Capital
Burlington,
Vermont
|
+$2.22M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Adage Capital Partners
Boston,
Massachusetts
|
-$14.1M |
| 2 |
MB
MPM BioImpact
Boston,
Massachusetts
|
-$10.1M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
-$4.79M |
| 4 |
Millennium Management
New York
|
-$4.3M |
| 5 |
SAM
Sectoral Asset Management
Montreal,
Quebec, Canada
|
-$3.91M |
SLDB Hedge Fund Activity: Q4 2025 in Review
130 of the 8,229 institutional investors tracked by Wall St. Rank reported a position in Solid Biosciences (SLDB) for Q4 2025, worth a combined $459M — down 8.6% from $502M a quarter earlier.
Buyers outnumbered sellers: 14 funds opened new SLDB positions and 11 closed out — a net gain of 3 holders — while 36 added to existing stakes and 47 trimmed.
The largest buyer was Vestal Point Capital, adding an estimated $15.4M. The largest seller was Adage Capital Partners, cutting an estimated $14.1M.
- 130 institutional investors held Solid Biosciences (SLDB) as of Q4 2025, up from 127 in Q3 2025.
- Funds reported $459M of Solid Biosciences stock for Q4 2025, down 8.6% quarter-over-quarter.
- 14 funds opened new Solid Biosciences positions in Q4 2025 and 11 closed out, a net change of +3 holders.
- The largest Solid Biosciences buyer in Q4 2025 was Vestal Point Capital, an estimated $15.4M added.
- The largest Solid Biosciences seller in Q4 2025 was Adage Capital Partners, an estimated $14.1M sold.
Based on aggregated 13F filings for Q4 2025.