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Schrodinger

Name Holding Trade Value Shares
Change
Change in
Stake
Gates Foundation Trust
1
Gates Foundation Trust
Washington
$301M +$264M +6,981,665 New
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$69M +$60.5M +1,601,047 New
DM
3
Deerfield Management
New York
$58M +$50.8M +1,346,167 New
Fidelity Investments
4
Fidelity Investments
Massachusetts
$57M +$49.9M +1,322,428 New
BAMCO Inc
5
BAMCO Inc
New York
$41M +$35.9M +950,014 New
VCM
6
Valiant Capital Management
California
$40M +$35M +927,890 New
AG
7
Artal Group
Luxembourg
$38.7M +$33.9M +897,445 New
BlackRock
8
BlackRock
New York
$33M +$28.9M +764,149 New
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$32.6M +$28.5M +755,085 New
LCM
10
Laurion Capital Management
New York
$32.1M +$28.1M +745,194 New
Vanguard Group
11
Vanguard Group
Pennsylvania
$31.8M +$27.8M +737,299 New
CS
12
Credit Suisse
Switzerland
$30.2M +$26.4M +700,038 New
Morgan Stanley
13
Morgan Stanley
New York
$22.9M +$20.1M +531,385 New
Capital International Investors
14
Capital International Investors
California
$21.6M +$18.9M +500,000 New
AI
15
Alphabet Inc
California
$19.3M +$16.9M +448,722 New
MICM
16
Matthews International Capital Management
California
$18.4M +$16.1M +427,300 New
DCM
17
Driehaus Capital Management
Illinois
$10.6M +$9.31M +246,680 New
State Street
18
State Street
Massachusetts
$10.6M +$9.27M +245,565 New
PA
19
Perceptive Advisors
New York
$10.5M +$9.44M +250,000 New
Massachusetts Financial Services
20
Massachusetts Financial Services
Massachusetts
$8.69M +$7.61M +201,607 New
BCPEMI
21
Bain Capital Public Equity Management II
Massachusetts
$7.83M +$6.86M +181,605 New
Northern Trust
22
Northern Trust
Illinois
$6.49M +$5.68M +150,537 New
ITP
23
Iron Triangle Partners
Connecticut
$6.47M +$5.66M +150,000 New
Citadel Advisors
24
Citadel Advisors
Florida
$4.34M +$3.8M +100,655 New
Geode Capital Management
25
Geode Capital Management
Massachusetts
$3.49M +$3.06M +80,988 New