Scilex Holding
SCLX
81 hedge funds and large institutions have $13.7M invested in Scilex Holding in 2025 Q4 according to their latest regulatory filings, with 11 funds opening new positions, 12 increasing their positions, 15 reducing their positions, and 12 closing their positions.
3.84% more ownership
Funds ownership: 10.93% → 14.76% (+3.8%)
8% less first-time investments, than exits
New positions opened: 11 | Existing positions closed: 12
2% less funds holding
Funds holding: 83 → 81 (-2)
9% less capital invested
Capital invested by funds: $15M → $13.7M (-$1.31M)
20% less repeat investments, than reductions
Existing positions increased: 12 | Existing positions reduced: 15
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
AC
Armistice Capital
New York
|
+$6.94M |
| 2 |
6CM
683 Capital Management
New York
|
+$461K |
| 3 |
XT
XTX Topco
George Town,
Cayman Islands
|
+$345K |
| 4 |
Citigroup
New York
|
+$335K |
| 5 |
Renaissance Technologies
New York
|
+$326K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Geode Capital Management
Boston,
Massachusetts
|
-$1.46M |
| 2 |
HF
HRT Financial
New York
|
-$627K |
| 3 |
UBS Group
Zurich,
Switzerland
|
-$234K |
| 4 |
Jane Street
New York
|
-$227K |
| 5 |
QCM
Quantinno Capital Management
New York
|
-$215K |
SCLX Hedge Fund Activity: Q4 2025 in Review
81 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Scilex Holding (SCLX) for Q4 2025, worth a combined $13.7M — down 8.7% from $15M a quarter earlier.
Sellers outnumbered buyers: 12 funds closed out of SCLX and 11 opened new positions — a net loss of 1 holder — while 15 trimmed existing stakes and 12 added.
The largest buyer was Armistice Capital, adding an estimated $6.94M. The largest seller was Geode Capital Management, exiting entirely with an estimated $1.46M sold.
- 81 institutional investors held Scilex Holding (SCLX) as of Q4 2025, down from 83 in Q3 2025.
- Funds reported $13.7M of Scilex Holding stock for Q4 2025, down 8.7% quarter-over-quarter.
- 11 funds opened new Scilex Holding positions in Q4 2025 and 12 closed out, a net change of -1 holder.
- The largest Scilex Holding buyer in Q4 2025 was Armistice Capital, an estimated $6.94M added.
- The largest Scilex Holding seller in Q4 2025 was Geode Capital Management, an estimated $1.46M sold.
Based on aggregated 13F filings for Q4 2025.