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Scilex Holding

83 hedge funds and large institutions have $15M invested in Scilex Holding in 2025 Q3 according to their latest regulatory filings, with 24 funds opening new positions, 12 increasing their positions, 15 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

302% more capital invested

Capital invested by funds: $3.72M → $15M (+$11.2M)

140% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 10

20% more funds holding

Funds holding: 6983 (+14)

1.79% more ownership

Funds ownership: 9.14%10.93% (+1.8%)

20% less repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 15

Holders
83
Holders Change
+14
Holders Change %
+20.29%
% of All Funds
1.09%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
24
Increased
12
Reduced
15
Closed
10
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$5.56M -$201K -11,890 -4%
BlackRock
2
BlackRock
New York
$1.94M -$574K -33,950 -26%
Geode Capital Management
3
Geode Capital Management
Massachusetts
$1.46M +$208K +12,300 +20%
AC
4
Armistice Capital
New York
$1.3M +$1.12M +66,000 New
State Street
5
State Street
Massachusetts
$658K +$365K +21,545 +181%
HF
6
HRT Financial
New York
$627K +$540K +31,908 New
UBS Group
7
UBS Group
Switzerland
$505K +$122K +7,224 +39%
Morgan Stanley
8
Morgan Stanley
New York
$456K +$86.3K +5,102 +28%
Renaissance Technologies
9
Renaissance Technologies
New York
$377K +$324K +19,164 New
ATPW
10
Ashton Thomas Private Wealth
Arizona
$354K +$304K +17,989 New
Bank of America
11
Bank of America
North Carolina
$342K +$132K +7,783 +81%
Northern Trust
12
Northern Trust
Illinois
$298K +$256K +15,157 New
DLHL
13
Donald L. Hagan LLC
Florida
$234K +$201K +11,873 New
Jane Street
14
Jane Street
New York
$227K +$195K +11,532 New
QCM
15
Quantinno Capital Management
New York
$215K -$42.7K -2,524 -19%
BNP Paribas Financial Markets
16
BNP Paribas Financial Markets
France
$146K +$82.3K +4,864 +190%
Barclays
17
Barclays
United Kingdom
$79.7K -$26K -1,534 -27%
CFD
18
Creative Financial Designs
Indiana
$36.5K +$31.4K +1,853 New
Jones Financial Companies
19
Jones Financial Companies
Missouri
$29K +$16.3K +964 +3,213%
MIM
20
MetLife Investment Management
New Jersey
$21.5K -$17 -1 -0.1%
TRCT
21
Tower Research Capital (TRC)
New York
$20.8K +$17.3K +1,023 +2,923%
Deutsche Bank
22
Deutsche Bank
Germany
$15.7K
VCM
23
Versant Capital Management
Arizona
$15K
MA
24
MCF Advisors
Kentucky
$9.33K +$8.02K +474 New
AWM
25
Activest Wealth Management
Florida
$5.94K

SCLX Hedge Fund Activity: Q3 2025 in Review

83 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Scilex Holding (SCLX) for Q3 2025, worth a combined $15M — up 302% from $3.72M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new SCLX positions and 10 closed out — a net gain of 14 holders — while 12 added to existing stakes and 15 trimmed.

The largest buyer was Armistice Capital, opening a new position worth an estimated $1.12M. The largest seller was BlackRock, cutting an estimated $574K.

  • 83 institutional investors held Scilex Holding (SCLX) as of Q3 2025, up from 69 in Q2 2025.
  • Funds reported $15M of Scilex Holding stock for Q3 2025, up 302% quarter-over-quarter.
  • 24 funds opened new Scilex Holding positions in Q3 2025 and 10 closed out, a net change of +14 holders.
  • The largest Scilex Holding buyer in Q3 2025 was Armistice Capital, an estimated $1.12M added.
  • The largest Scilex Holding seller in Q3 2025 was BlackRock, an estimated $574K sold.

Based on aggregated 13F filings for Q3 2025.