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Scilex Holding
SCLX

69 hedge funds and large institutions have $3.72M invested in Scilex Holding in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 12 increasing their positions, 20 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

8.61% more ownership

Funds ownership: 0.53% → 9.14% (+8.6%)

15% less funds holding

Funds holding: 81 → 69 (-12)

24% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 45

40% less repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 20

67% less capital invested

Capital invested by funds: $11.3M → $3.72M (-$7.55M)

Holders
69
Holders Change
-12
Holders Change %
-14.81%
% of All Funds
0.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
34
Increased
12
Reduced
20
Closed
45
Calls
$78K
Puts
–
Net Calls
+$78K
Net Calls Change
+$75K

Top Buyers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
+$711K
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$89.5K
3
QCM
Quantinno Capital Management
New York
+$76.1K
4
Morgan Stanley
Morgan Stanley
New York
+$48K
5
Citadel Advisors
Citadel Advisors
Florida
+$47.4K

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$3.43M
2
State Street
State Street
Massachusetts
-$1.16M
3
BlackRock
BlackRock
New York
-$340K
4
Northern Trust
Northern Trust
Illinois
-$334K
5
RCM
RA Capital Management
Massachusetts
-$258K
Name Holding Trade Value Shares
Change 		Change in
Stake
Bank of New York Mellon
101
Bank of New York Mellon
New York
– -$3.93K -452 Closed
BB
102
Busey Bank
Illinois
– -$3.8K -437 Closed
Handelsbanken Fonder
103
Handelsbanken Fonder
Sweden
– -$3K -319 Closed
CI Investments Inc
104
CI Investments Inc
Ontario, Canada
– -$2K -234 Closed
Lazard Asset Management
105
Lazard Asset Management
New York
– -$1K -162 Closed
STB
106
S&T Bank
Pennsylvania
– -$1.36K -157 Closed
AIP
107
Ameritas Investment Partners
Nebraska
– -$1.29K -149 Closed
Public Employees Retirement Association of Colorado
108
Public Employees Retirement Association of Colorado
Colorado
– -$1K -135 Closed
SC
109
Stephens Consulting
Michigan
– -$61 -7 Closed
TCOV
110
Trust Company of Vermont
Vermont
– -$7 -1 Closed
Federated Hermes
111
Federated Hermes
Pennsylvania
– -$1 – –
PNC Financial Services Group
112
PNC Financial Services Group
Pennsylvania
– -$2 – –
TFGT
113
TS Financial Group (TSFG)
Illinois
– +$6 +1 New
NWM
114
Navigoe Wealth Management
California
– +$45 +8 New
AW
115
Avion Wealth
Texas
– +$113 +20 +35%
1 2 3 4
5

SCLX Hedge Fund Activity: Q2 2025 in Review

69 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Scilex Holding (SCLX) for Q2 2025, worth a combined $3.72M — down 67% from $11.3M a quarter earlier.

Sellers outnumbered buyers: 45 funds closed out of SCLX and 34 opened new positions — a net loss of 11 holders — while 20 trimmed existing stakes and 12 added.

The largest buyer was Vanguard Group, adding an estimated $711K. The largest seller was Armistice Capital, exiting entirely with an estimated $3.43M sold.

  • 69 institutional investors held Scilex Holding (SCLX) as of Q2 2025, down from 81 in Q1 2025.
  • Funds reported $3.72M of Scilex Holding stock for Q2 2025, down 67% quarter-over-quarter.
  • 34 funds opened new Scilex Holding positions in Q2 2025 and 45 closed out, a net change of -11 holders.
  • The largest Scilex Holding buyer in Q2 2025 was Vanguard Group, an estimated $711K added.
  • The largest Scilex Holding seller in Q2 2025 was Armistice Capital, an estimated $3.43M sold.

Based on aggregated 13F filings for Q2 2025.