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Scilex Holding
SCLX

69 hedge funds and large institutions have $3.72M invested in Scilex Holding in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 12 increasing their positions, 20 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

8.61% more ownership

Funds ownership: 0.53% → 9.14% (+8.6%)

15% less funds holding

Funds holding: 81 → 69 (-12)

24% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 45

40% less repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 20

67% less capital invested

Capital invested by funds: $11.3M → $3.72M (-$7.55M)

Holders
69
Holders Change
-12
Holders Change %
-14.81%
% of All Funds
0.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
34
Increased
12
Reduced
20
Closed
45
Calls
$78K
Puts
–
Net Calls
+$78K
Net Calls Change
+$75K

Top Buyers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
+$711K
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$89.5K
3
QCM
Quantinno Capital Management
New York
+$76.1K
4
Morgan Stanley
Morgan Stanley
New York
+$48K
5
Citadel Advisors
Citadel Advisors
Florida
+$47.4K

Top Sellers

Rank Fund Capital Flow
1
AC
Armistice Capital
New York
-$3.43M
2
State Street
State Street
Massachusetts
-$1.16M
3
BlackRock
BlackRock
New York
-$340K
4
Northern Trust
Northern Trust
Illinois
-$334K
5
RCM
RA Capital Management
Massachusetts
-$258K
Name Holding Trade Value Shares
Change 		Change in
Stake
Prudential Financial
76
Prudential Financial
New Jersey
– -$38.3K -4,401 Closed
Goldman Sachs
77
Goldman Sachs
New York
– -$33.9K -3,896 Closed
Axa
78
Axa
France
– -$27.1K -3,119 Closed
Jane Street
79
Jane Street
New York
– -$25.9K -2,976 Closed
Susquehanna International Group
80
Susquehanna International Group
Pennsylvania
– -$15.7K -2,772 Closed
California State Teachers Retirement System (CalSTRS)
81
California State Teachers Retirement System (CalSTRS)
California
– -$20.1K -2,316 Closed
Qube Research & Technologies (QRT)
82
Qube Research & Technologies (QRT)
United Kingdom
– -$19.2K -2,205 Closed
Renaissance Technologies
83
Renaissance Technologies
New York
– -$16.5K -1,900 Closed
State of Wisconsin Investment Board
84
State of Wisconsin Investment Board
Wisconsin
– -$15.8K -1,819 Closed
UBS AM
85
UBS AM
Illinois
– -$11.1K -1,281 Closed
Two Sigma Investments
86
Two Sigma Investments
New York
– -$11K -1,270 Closed
Millennium Management
87
Millennium Management
New York
– -$8.86K -1,018 Closed
EFM
88
E Fund Management
China
– -$7.81K -898 Closed
CFO
89
Collective Family Office
Pennsylvania
– -$7.78K -894 Closed
CF
90
Corebridge Financial
Texas
– -$7.65K -879 Closed
IWM
91
IHT Wealth Management
Illinois
– -$7.46K -857 Closed
Fidelity Investments
92
Fidelity Investments
Massachusetts
– -$7.22K -831 Closed
Simplex Trading
93
Simplex Trading
Illinois
– -$6K -708 Closed
Two Sigma Advisers
94
Two Sigma Advisers
New York
– -$5.72K -657 Closed
Squarepoint
95
Squarepoint
New York
– -$5.14K -591 Closed
Invesco
96
Invesco
Georgia
– -$5.13K -590 Closed
Teacher Retirement System of Texas
97
Teacher Retirement System of Texas
Texas
– -$4.96K -570 Closed
AAS
98
Avantax Advisory Services
Texas
– -$4.91K -565 Closed
VIA
99
Virtus Investment Advisers
Connecticut
– -$4.24K -513 Closed
ASRS
100
Arizona State Retirement System
Arizona
– -$4.45K -512 Closed
1 2 3
4
5

SCLX Hedge Fund Activity: Q2 2025 in Review

69 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Scilex Holding (SCLX) for Q2 2025, worth a combined $3.72M — down 67% from $11.3M a quarter earlier.

Sellers outnumbered buyers: 45 funds closed out of SCLX and 34 opened new positions — a net loss of 11 holders — while 20 trimmed existing stakes and 12 added.

The largest buyer was Vanguard Group, adding an estimated $711K. The largest seller was Armistice Capital, exiting entirely with an estimated $3.43M sold.

  • 69 institutional investors held Scilex Holding (SCLX) as of Q2 2025, down from 81 in Q1 2025.
  • Funds reported $3.72M of Scilex Holding stock for Q2 2025, down 67% quarter-over-quarter.
  • 34 funds opened new Scilex Holding positions in Q2 2025 and 45 closed out, a net change of -11 holders.
  • The largest Scilex Holding buyer in Q2 2025 was Vanguard Group, an estimated $711K added.
  • The largest Scilex Holding seller in Q2 2025 was Armistice Capital, an estimated $3.43M sold.

Based on aggregated 13F filings for Q2 2025.