Sana Biotechnology
SANA
203 hedge funds and large institutions have $649M invested in Sana Biotechnology in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 69 increasing their positions, 48 reducing their positions, and 21 closing their positions.
208% more call options, than puts
Call options by funds: $3.54M | Put options by funds: $1.15M
129% more first-time investments, than exits
New positions opened: 48 | Existing positions closed: 21
44% more repeat investments, than reductions
Existing positions increased: 69 | Existing positions reduced: 48
14% more funds holding
Funds holding: 178 → 203 (+25)
12% more capital invested
Capital invested by funds: $582M → $649M (+$67M)
0% more funds holding in top 10
Funds holding in top 10: 3 → 3 (0)
9.04% less ownership
Funds ownership: 68.82% → 59.78% (-9%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
+$13.4M |
| 2 |
Balyasny Asset Management
Chicago,
Illinois
|
+$7.52M |
| 3 |
State Street
Boston,
Massachusetts
|
+$6.15M |
| 4 |
Vanguard Group
Malvern,
Pennsylvania
|
+$5.94M |
| 5 |
IHAM
Integral Health Asset Management
New York
|
+$4.48M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Citadel Advisors
Miami,
Florida
|
-$29.3M |
| 2 |
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
-$21.6M |
| 3 |
BBA
Baker Bros. Advisors
New York
|
-$7.7M |
| 4 |
JP Morgan Chase
New York
|
-$5.91M |
| 5 |
Millennium Management
New York
|
-$4.46M |
SANA Hedge Fund Activity: Q4 2025 in Review
203 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Sana Biotechnology (SANA) for Q4 2025, worth a combined $649M — up 12% from $582M a quarter earlier.
Buyers outnumbered sellers: 48 funds opened new SANA positions and 21 closed out — a net gain of 27 holders — while 69 added to existing stakes and 48 trimmed.
The largest buyer was BlackRock, adding an estimated $13.4M. The largest seller was Citadel Advisors, cutting an estimated $29.3M.
- 203 institutional investors held Sana Biotechnology (SANA) as of Q4 2025, up from 178 in Q3 2025.
- Funds reported $649M of Sana Biotechnology stock for Q4 2025, up 12% quarter-over-quarter.
- 48 funds opened new Sana Biotechnology positions in Q4 2025 and 21 closed out, a net change of +27 holders.
- The largest Sana Biotechnology buyer in Q4 2025 was BlackRock, an estimated $13.4M added.
- The largest Sana Biotechnology seller in Q4 2025 was Citadel Advisors, an estimated $29.3M sold.
Based on aggregated 13F filings for Q4 2025.