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Sana Biotechnology

178 hedge funds and large institutions have $582M invested in Sana Biotechnology in 2025 Q3 according to their latest regulatory filings, with 46 funds opening new positions, 66 increasing their positions, 36 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

119% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 21

83% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 36

46% more capital invested

Capital invested by funds: $398M → $582M (+$184M)

15% more funds holding

Funds holding: 155178 (+23)

4.3% more ownership

Funds ownership: 64.52%68.82% (+4.3%)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

11% less call options, than puts

Call options by funds: $1.48M | Put options by funds: $1.66M

Holders
178
Holders Change
+23
Holders Change %
+14.84%
% of All Funds
2.34%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
46
Increased
66
Reduced
36
Closed
21
Calls
$1.48M
Puts
$1.66M
Net Calls
-$183K
Net Calls Change
-$973K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$133M +$13M +3,598,059 +11%
FP
2
Flagship Pioneering
Massachusetts
$88.8M
Baillie Gifford & Co
3
Baillie Gifford & Co
United Kingdom
$40.6M +$4.96M +1,371,775 +14%
BlackRock
4
BlackRock
New York
$39.9M +$1.33M +367,236 +3%
Canada Pension Plan Investment Board
5
Canada Pension Plan Investment Board
Ontario, Canada
$36.1M
Vanguard Group
6
Vanguard Group
Pennsylvania
$32.4M +$5.49M +1,517,474 +20%
State Street
7
State Street
Massachusetts
$23.7M +$13.8M +3,820,417 +134%
Citadel Advisors
8
Citadel Advisors
Florida
$23.3M +$13M +3,596,930 +122%
MG
9
Marex Group
$13.6M +$18.1K +5,000 +0.1%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$12.2M +$520K +143,741 +4%
AI
11
Alphabet Inc
California
$9.98M
JP Morgan Chase
12
JP Morgan Chase
New York
$7.58M +$4.97M +1,375,029 +181%
BBA
13
Baker Bros. Advisors
New York
$7.21M
IHAM
14
Integral Health Asset Management
New York
$7.1M +$1.81M +500,000 +33%
Renaissance Technologies
15
Renaissance Technologies
New York
$7.07M +$6.47M +1,788,788 +878%
CM
16
Crestline Management
Texas
$6.46M -$2.17M -600,000 -25%
Millennium Management
17
Millennium Management
New York
$5.75M +$2.97M +822,423 +103%
UBS Group
18
UBS Group
Switzerland
$5.13M +$1.08M +298,551 +26%
WP
19
Woodline Partners
California
$4.89M +$2.16M +597,014 +76%
Northern Trust
20
Northern Trust
Illinois
$4.68M +$594K +164,182 +14%
Charles Schwab
21
Charles Schwab
California
$4.52M +$674K +186,388 +17%
AQR Capital Management
22
AQR Capital Management
Connecticut
$4.2M -$631K -174,581 -13%
Bank of America
23
Bank of America
North Carolina
$3.26M +$119K +32,814 +4%
Morgan Stanley
24
Morgan Stanley
New York
$3.11M -$2.18M -603,290 -41%
OFM
25
Omega Fund Management
Massachusetts
$3M

SANA Hedge Fund Activity: Q3 2025 in Review

178 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Sana Biotechnology (SANA) for Q3 2025, worth a combined $582M — up 46% from $398M a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new SANA positions and 21 closed out — a net gain of 25 holders — while 66 added to existing stakes and 36 trimmed.

The largest buyer was State Street, adding an estimated $13.8M. The largest seller was T. Rowe Price Associates, cutting an estimated $8.72M.

  • 178 institutional investors held Sana Biotechnology (SANA) as of Q3 2025, up from 155 in Q2 2025.
  • Funds reported $582M of Sana Biotechnology stock for Q3 2025, up 46% quarter-over-quarter.
  • 46 funds opened new Sana Biotechnology positions in Q3 2025 and 21 closed out, a net change of +25 holders.
  • The largest Sana Biotechnology buyer in Q3 2025 was State Street, an estimated $13.8M added.
  • The largest Sana Biotechnology seller in Q3 2025 was T. Rowe Price Associates, an estimated $8.72M sold.

Based on aggregated 13F filings for Q3 2025.