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Sana Biotechnology
SANA

161 hedge funds and large institutions have $252M invested in Sana Biotechnology in 2025 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 54 increasing their positions, 41 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more call options, than puts

Call options by funds: $1.06M | Put options by funds: $712K

32% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 41

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

3% less capital invested

Capital invested by funds: $258M → $252M (-$6.75M)

9% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 32

2% less funds holding

Funds holding: 164 → 161 (-3)

4.44% less ownership

Funds ownership: 70.78% → 66.34% (-4.4%)

Holders
161
Holders Change
-3
Holders Change %
-1.83%
% of All Funds
2.16%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
29
Increased
54
Reduced
41
Closed
32
Calls
$1.06M
Puts
$712K
Net Calls
+$353K
Net Calls Change
-$1.61M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$6.14M
2
CC
Clearline Capital
New York
+$1.15M
3
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$990K
4
Deutsche Bank
Deutsche Bank
Germany
+$871K
5
UBS Group
UBS Group
Switzerland
+$783K

Top Sellers

1
Vanguard Group
Vanguard Group
Pennsylvania
-$8.06M
2
State Street
State Street
Massachusetts
-$3.4M
3
Morgan Stanley
Morgan Stanley
New York
-$3.03M
4
BCM
Boxer Capital Management
California
-$2.52M
5
Corient Private Wealth
Corient Private Wealth
Florida
-$2.44M
Name Holding Trade Value Shares
Change 		Change in
Stake
Deutsche Bank
26
Deutsche Bank
Germany
$1.12M +$871K +311,692 +88%
AQR Capital Management
27
AQR Capital Management
Connecticut
$963K +$532K +190,483 +50%
Goldman Sachs
28
Goldman Sachs
New York
$930K -$1.26M -451,246 -45%
Bank of America
29
Bank of America
North Carolina
$888K -$1.69M -602,961 -53%
Barclays
30
Barclays
United Kingdom
$842K +$511K +182,960 +57%
Jane Street
31
Jane Street
New York
$760K +$236K +84,306 +23%
CC
32
Clearline Capital
New York
$690K +$1.15M +410,535 New
Balyasny Asset Management
33
Balyasny Asset Management
Illinois
$595K +$990K +354,238 New
N
34
Nuveen
North Carolina
$589K – – –
Bank of New York Mellon
35
Bank of New York Mellon
New York
$578K +$20.2K +7,230 +2%
Susquehanna International Group
36
Susquehanna International Group
Pennsylvania
$533K +$620K +221,643 +232%
Citigroup
37
Citigroup
New York
$528K +$132K +47,059 +18%
Corient Private Wealth
38
Corient Private Wealth
Florida
$523K -$2.44M -871,204 -74%
TD Asset Management
39
TD Asset Management
Ontario, Canada
$519K -$266K -95,314 -24%
Manulife (Manufacturers Life Insurance)
40
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$487K -$50.7K -18,127 -6%
Skandinaviska Enskilda Banken (SEB)
41
Skandinaviska Enskilda Banken (SEB)
Sweden
$483K +$279K +99,801 +53%
UBS AM
42
UBS AM
Illinois
$479K +$15.8K +5,642 +2%
Mirae Asset Global ETFs Holdings
43
Mirae Asset Global ETFs Holdings
Hong Kong
$458K -$22.5K -8,061 -3%
CRAM
44
Compass Rose Asset Management
New York
$420K – – –
Swiss National Bank
45
Swiss National Bank
Switzerland
$400K – – –
Millennium Management
46
Millennium Management
New York
$398K -$1.37M -491,772 -67%
CGL
47
Clarius Group LLC
Washington
$357K +$280K +100,000 +89%
Marshall Wace
48
Marshall Wace
United Kingdom
$355K +$531K +189,905 +891%
Rafferty Asset Management
49
Rafferty Asset Management
New York
$328K -$332K -118,716 -38%
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$306K +$26.2K +9,359 +5%
1
2
3 4 5

SANA Hedge Fund Activity: Q1 2025 in Review

161 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Sana Biotechnology (SANA) for Q1 2025, worth a combined $252M — down 2.6% from $258M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SANA and 29 opened new positions — a net loss of 3 holders — while 41 trimmed existing stakes and 54 added.

The largest buyer was Citadel Advisors, adding an estimated $6.14M. The largest seller was Vanguard Group, cutting an estimated $8.06M.

  • 161 institutional investors held Sana Biotechnology (SANA) as of Q1 2025, down from 164 in Q4 2024.
  • Funds reported $252M of Sana Biotechnology stock for Q1 2025, down 2.6% quarter-over-quarter.
  • 29 funds opened new Sana Biotechnology positions in Q1 2025 and 32 closed out, a net change of -3 holders.
  • The largest Sana Biotechnology buyer in Q1 2025 was Citadel Advisors, an estimated $6.14M added.
  • The largest Sana Biotechnology seller in Q1 2025 was Vanguard Group, an estimated $8.06M sold.

Based on aggregated 13F filings for Q1 2025.